SCHEMBL424584

SCHEMBL424584

NCC(=O)OC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.65
MEN1 O00255 2/20 0.65
LMNA P02545 2/20 0.65
KMT2A Q03164 2/20 0.65
KDM4E B2RXH2 2/20 0.65
MPO P05164 1/20 0.65
TSHR P16473 1/20 0.65
BLM P54132 1/20 0.65
PMP22 Q01453 1/20 0.65
HIF1A Q16665 1/20 0.65
TACR1 P25103 2/20 0.60
HTR2A P28223 2/20 0.52
ADRB1 P08588 1/20 0.52
HTR1A P08908 1/20 0.52
ADRA2A P08913 1/20 0.52
SLC6A2 P23975 1/20 0.52
HTR1D P28221 1/20 0.52
HTR1B P28222 1/20 0.52
HTR2C P28335 1/20 0.52
HTR1E P28566 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289044 0.91 MAPT (0.74) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL475351 0.91 MAPT (0.74) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL2425346 0.89 MAPT (0.64) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL15093172 0.89 MAPT (0.64) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL21059260 0.88 MAPT (0.70) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL29701302 0.88 MAPT (0.62) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL28543938 0.88 MAPT (0.62) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL598475 0.88 MAPT (0.62) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL17503190 0.87 MAPT (0.72) MAPTMEN1LMNAKMT2AKDM4E
SCHEMBL1640627 0.87 MAPT (0.68) MAPTMEN1LMNAKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106478771-A A kind of synthetic method of amino acid neural tetrapeptide 李世军 2017-03-08 CN claimed
CN-106279354-A A kind of synthetic method of amino acid neural dipeptides 温州医科大学 2017-01-04 CN claimed
CN-116507349-A Probiotic bacillus compositions and methods of use 生物编辑有限责任公司 2023-07-28 CN disclosed
EP-4017281-A1 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2022-06-29 EP disclosed
CN-113683661-B Dual-response dipeptide supramolecular polymer and preparation method and application thereof 济宁医学院 2022-03-11 CN disclosed
CN-113683661-B Dual-response dipeptide supramolecular polymer and preparation method and application thereof 济宁医学院 2022-03-11 CN disclosed
CN-113683661-A Dual-response dipeptide supramolecular polymer and preparation method and application thereof 济宁医学院 2021-11-23 CN disclosed
CN-113683661-A Dual-response dipeptide supramolecular polymer and preparation method and application thereof 济宁医学院 2021-11-23 CN disclosed
WO-2021127701-A1 PET FOOD COMPOSITIONS HILL'S PET NUTRITION, INC. (US) 2021-06-24 WO disclosed
US-10456736-B2 Method and apparatus for purification and treatment of air PALOZA LLC (US) 2019-10-29 US disclosed
EP-3277083-A1 ORGAN PRESERVATION COMPOSITION TX Innovations B.V. (NL) 2018-02-07 EP disclosed
EP-0892054-A1 Clostridium perfringens vaccine Akzo Nobel N.V. (NL) 1999-01-20 EP disclosed
US-5846942-A Cholecystokinin antagonists, their preparation and therapeutic use WARNER-LAMBERT COMPANY (US) 1998-12-08 US disclosed
US-5593967-A Cholecystokinin antagonists, their preparation and therapeutic use WARNER-LAMBERT COMPANY (US) 1997-01-14 US disclosed
EP-0726936-A1 LIQUID DETERGENTS WITH ORTHO-SUBSTITUTED PHENYLBORONIC ACIDS FOR INHIBITION OF PROTEOLYTIC ENZYME THE PROCTER & GAMBLE COMPANY (US) 1996-08-21 EP disclosed
WO-1995012655-A1 LIQUID DETERGENTS WITH ORTHO-SUBSTITUTED PHENYLBORONIC ACIDS FOR INHIBITION OF PROTEOLYTIC ENZYME THE PROCTER & GAMBLE COMPANY (US) 1995-05-11 WO disclosed
EP-0547178-A4 NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE WARNER LAMBERT CO (US) 1994-07-06 EP disclosed
EP-0547178-A1 NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE WARNER-LAMBERT COMPANY (US) 1993-06-23 EP disclosed
WO-1992004045-A1 NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE WARNER-LAMBERT COMPANY (US) 1992-03-19 WO disclosed
US-4798778-A ETHYLENE POLYMER WITH CARBOXY ACID DERIVATIVE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-01-17 US disclosed