SCHEMBL4245945

SCHEMBL4245945

CN(CC1C2CCC1CN(Cc1ccccc1)C2)C(=O)Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 1/20 0.54
CCR5 P51681 1/20 0.47
MLNR O43193 2/20 0.46
KCNH2 Q12809 1/20 0.46
S1PR1 P21453 3/20 0.44
CYP3A4 P08684 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM3 P20309 1/20 0.44
S1PR5 Q9H228 3/20 0.43
CHRM4 P08173 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4241259 0.85 CHRM4 (0.54) CHRM4
SCHEMBL4245847 0.81 USP30 (0.67) USP30CCR5
SCHEMBL4240897 0.79 MEN1 (0.54) MLNRS1PR1CYP3A4S1PR5CHRM4
SCHEMBL4248205 0.77 BACE1 (0.55)
SCHEMBL19017605 0.74 USP30 (0.64) USP30CCR5CHRM3
SCHEMBL3226713 0.72 CHRM3 (0.51) CHRM2CHRM3
SCHEMBL4250553 0.72 ACHE (0.46) S1PR1S1PR5
SCHEMBL4245976 0.71 DRD2 (0.58) CHRM4
SCHEMBL7242578 0.71 FUCA1 (0.50) S1PR1S1PR5
SCHEMBL18987268 0.70 USP30 (0.58) USP30CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090012116-A1 Muscarinic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2009-01-08 US claimed
EP-1904446-A2 AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS Ranbaxy Laboratories Limited (IN) 2008-04-02 EP claimed
WO-2007007282-A2 AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2007-01-18 WO claimed
US-20090012116-A1 Muscarinic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2009-01-08 US disclosed
EP-1904446-A2 AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS Ranbaxy Laboratories Limited (IN) 2008-04-02 EP disclosed
WO-2007007282-A2 AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2007-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012116-A1 Muscarinic Receptor Antagonists CHRM3, CHRM2, CHRM5 USP30 1533/4885CCR5 355/4885MLNR 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.