Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014405 | 0.85 | FUCA1 (0.53) | FUCA1BCHEGRIN2BS1PR1S1PR5 | |
| SCHEMBL3527474 | 0.85 | GRIN2B (0.45) | FUCA1BCHEGRIN2BS1PR1S1PR5 | |
| SCHEMBL4136255 | 0.84 | OPRM1 (0.46) | FUCA1GRIN2BACHEOPRM1 | |
| SCHEMBL4141323 | 0.83 | ACHE (0.44) | FUCA1GRIN2BS1PR1S1PR5DRD2 | |
| SCHEMBL4149481 | 0.83 | CHRM3 (0.46) | FUCA1GRIN2BACHE | |
| SCHEMBL7248714 | 0.83 | FUCA1 (0.46) | FUCA1BCHEGRIN2BS1PR1S1PR5 | |
| SCHEMBL4132636 | 0.83 | KCNH2 (0.43) | FUCA1GRIN2BS1PR1S1PR5DRD2 | |
| SCHEMBL2300893 | 0.83 | ACHE (0.49) | FUCA1BCHEDRD2SIGMAR1ACHE | |
| SCHEMBL13853360 | 0.79 | OPRM1 (0.53) | GRIN2BS1PR1S1PR5OPRM1KDM4E | |
| SCHEMBL4197879 | 0.79 | OPRM1 (0.53) | GRIN2BS1PR1S1PR5OPRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559162-B2 | Electrophysiological activity | ASTRAZENECA AB (SE) | 2003-05-06 | — | — | US | disclosed |
| US-20020137766-A1 | Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137766-A1 | Azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias | KCNH1, KCNH2, KCNH3 | FUCA1 2408/4885BCHE 1251/4885GRIN2B 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.