Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066851 | 0.84 | HRH1 (0.50) | HRH1HTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL17077450 | 0.81 | SLC6A2 (0.50) | HTR1ASLC6A2SLC6A3ADRA2AADRA2B | |
| SCHEMBL17077451 | 0.81 | SLC6A2 (0.50) | HTR1ASLC6A2SLC6A3ADRA2AADRA2B | |
| Ethylene SCHEMBL27549603 | 0.81 | ALDH1A1 (0.56) | HTR1AADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL1780546 | 0.81 | HRH1 (0.62) | HRH1HTR1ASLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL23582983 | 0.80 | SLC6A2 (0.49) | HTR1ASLC6A2SLC6A3ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL17077567 | 0.80 | SLC6A2 (0.49) | HTR1ASLC6A2SLC6A3ADRA2AADRA2B | |
| SCHEMBL28754655 | 0.80 | SLC6A2 (0.55) | HTR1ASLC6A2SLC6A3SLC6A4HTR2A | |
| Ethylene SCHEMBL27857573 | 0.80 | ALDH1A1 (0.55) | HTR1AADRA2AADRA2BADRA2CKDM4E | |
| Hydrochloric Acid SCHEMBL4100905 | 0.79 | HRH1 (0.60) | HRH1HTR1ASLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-07-02 | — | — | US | disclosed |
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |
| EP-1328514-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034718-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | OPRM1, GRIN2C, GRIN3A | HRH1 42/4885HTR1A 373/4885SLC6A2 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.