Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353670 | 0.83 | KEAP1 (0.38) | CYP2D6CYP2C19CYP3A4SIGMAR1L3MBTL1 | |
| SCHEMBL7352978 | 0.81 | SMN1; SMN2 (0.36) | CYP2D6CYP3A4SIGMAR1L3MBTL1ALDH1A1 | |
| SCHEMBL16432068 | 0.68 | HRH3 (0.34) | HRH3TERTCYP1A2CYP3A4HRH1 | |
| SCHEMBL5466977 | 0.68 | HRH3 (0.69) | HRH3TERTCYP1A2SIGMAR1L3MBTL1 | |
| SCHEMBL134912 | 0.68 | HRH3 (0.69) | HRH3TERTCYP1A2SIGMAR1L3MBTL1 | |
| SCHEMBL23828671 | 0.68 | HRH3 (0.69) | HRH3TERTCYP1A2SIGMAR1L3MBTL1 | |
| SCHEMBL12826 | 0.68 | HRH3 (0.69) | HRH3TERTCYP1A2SIGMAR1L3MBTL1 | |
| SCHEMBL4786815 | 0.68 | HRH3 (0.69) | HRH3TERTCYP1A2SIGMAR1L3MBTL1 | |
| SCHEMBL16316121 | 0.67 | HRH3 (0.46) | HRH3TERTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1456056 | 0.67 | HRH3 (0.33) | HRH3TERTCYP1A2CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238760-A1 | ANTISPERMATOGENIC, SPERMICIDAL AND/OR ANTIFUNGAL COMPOSITION AND METHODS OF USING THE SAME | RESEARCH TRIANGLE INSTITUTE (US) | 2009-09-24 | — | — | US | claimed |
| EP-2007374-A2 | ANTISPERMATOGENIC, SPERMICIDAL AND/OR ANTIFUNGAL COMPOSITION AND METHODS OF USING THE SAME | RESEARCH TRIANGLE INSTITUTE (US) | 2008-12-31 | — | — | EP | claimed |
| WO-2007124353-A2 | ANTISPERMATOGENIC, SPERMICIDAL AND/OR ANTIFUNGAL COMPOSITION AND METHODS OF USING THE SAME | RESEARCH TRIANGLE INSTITUTE (US) | 2007-11-01 | — | — | WO | claimed |
| US-5446037-A | Antiallergens; elastase inhibitors | SYNPHAR LABORATORIES, INC. (CA) | 1995-08-29 | — | — | US | claimed |
| US-20090238760-A1 | ANTISPERMATOGENIC, SPERMICIDAL AND/OR ANTIFUNGAL COMPOSITION AND METHODS OF USING THE SAME | RESEARCH TRIANGLE INSTITUTE (US) | 2009-09-24 | — | — | US | disclosed |
| EP-2007374-A2 | ANTISPERMATOGENIC, SPERMICIDAL AND/OR ANTIFUNGAL COMPOSITION AND METHODS OF USING THE SAME | RESEARCH TRIANGLE INSTITUTE (US) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007124353-A2 | ANTISPERMATOGENIC, SPERMICIDAL AND/OR ANTIFUNGAL COMPOSITION AND METHODS OF USING THE SAME | RESEARCH TRIANGLE INSTITUTE (US) | 2007-11-01 | — | — | WO | disclosed |
| US-5446037-A | Antiallergens; elastase inhibitors | SYNPHAR LABORATORIES, INC. (CA) | 1995-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238760-A1 | ANTISPERMATOGENIC, SPERMICIDAL AND/OR ANTIFUNGAL COMPOSITION AND METHODS OF USING THE SAME | NASP, CATSPER1, ACR | HRH3 400/4885TERT 3235/4885CYP1A2 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.