⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424752 | 1.00 | — | — | |
| SCHEMBL10060050 | 1.00 | — | — | |
| SCHEMBL419252 | 0.80 | — | — | |
| SCHEMBL419251 | 0.80 | — | — | |
| SCHEMBL424063 | 0.79 | CHRNB2 (0.31) | — | |
| SCHEMBL424064 | 0.79 | CHRNB2 (0.31) | — | |
| SCHEMBL426320 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL426321 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL424144 | 0.76 | — | — | |
| SCHEMBL425614 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180604-B | Production method of 3-methyl-4-nitroiminotetrahydro-1, 3, 5-oxadiazine | 浙江中山化工集团股份有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-115385904-A | Green synthesis method of thiamethoxam | 内蒙古同创高科化学有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-110981866-B | Thiamethoxam production method and extracting agent | 邯郸市瑞田农药有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-110092783-B | Preparation method of thiamethoxam | 湖南化工研究院有限公司 | 2020-11-20 | — | — | CN | claimed |
| CN-111217765-A | Synthesis process of 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine | 宁夏东吴农化股份有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-110981866-A | Thiamethoxam production method and extracting agent | 邯郸市瑞田农药有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-106496215-B | High-yield green environment-friendly synthetic method of thiamethoxam | 邯郸市瑞田农药有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-107501256-B | Preparation method of high-purity thiamethoxam | 北京怡力生物科技有限公司 | 2020-03-31 | — | — | CN | claimed |
| CN-108164522-B | Synthetic method of thiamethoxam | 浙江永太科技股份有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-108164522-A | The synthetic method of Diacloden | 浙江永太科技股份有限公司 | 2018-06-15 | — | — | CN | claimed |
| WO-2015180585-A9 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2016-12-15 | — | — | WO | claimed |
| WO-2015180585-A1 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2015-12-03 | — | — | WO | claimed |
| EP-0850231-B1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | SYNGENTA PARTICIPATIONS AG (CH) | 2003-04-02 | — | — | EP | claimed |
| US-6187927-B1 | REACTING 2-CHLOROALLYLFORMAMIDE WITH DEHYDRATING, HALOGENATING, AND SULFURIZING AGENTS | NOVARTIS CROP PROTECTION, INC. | 2001-02-13 | — | — | US | claimed |
| CN-121850994-A | Thiamethoxam preparation process based on low-temperature reaction | 内蒙古立威生物科技有限公司 | 2026-04-14 | — | — | CN | disclosed |
| CN-121779391-A | Clean synthesis process of thiamethoxam with high yield | 内蒙古犇星化学有限公司 | 2026-04-03 | — | — | CN | disclosed |
| CN-117865907-A | Preparation method of high-quality oxadiazine | 宁夏贝利特生物科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-1998027074-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1998-06-25 | — | — | WO | disclosed |
| WO-1997010226-A1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | NOVARTIS AG (CH) | 1997-03-20 | — | — | WO | disclosed |
| EP-0580553-A2 | Oxadiazine derivatives | CIBA-GEIGY AG (CH) | 1994-01-26 | — | — | EP | disclosed |