SCHEMBL4247741

SCHEMBL4247741

CCOC(=O)/C=C(\Oc1ccccc1[N+](=O)[O-])C(=O)OCC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.45
CES2 O00748 1/20 0.45
ACHE P22303 1/20 0.45
CES1 P23141 1/20 0.45
ALDH1A1 P00352 7/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 3/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 1/20 0.43
RECQL P46063 2/20 0.42
NPC1 O15118 1/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
TTR P02766 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4252109 1.00 RAB9A (0.58) RAB9AL3MBTL1KDM4EPOLBCES2
SCHEMBL4247745 1.00 RAB9A (0.58) RAB9AL3MBTL1KDM4EPOLBCES2
SCHEMBL4252616 0.88 RAB9A (0.47) RAB9AL3MBTL1KDM4EPOLBALDH1A1
SCHEMBL4249056 0.88 RAB9A (0.47) RAB9AL3MBTL1KDM4EPOLBALDH1A1
SCHEMBL4249053 0.88 RAB9A (0.47) RAB9AL3MBTL1KDM4EPOLBALDH1A1
SCHEMBL4251557 0.86 RAB9A (0.46) RAB9AL3MBTL1KDM4EPOLBALDH1A1
SCHEMBL4254610 0.86 RAB9A (0.46) RAB9AL3MBTL1KDM4EPOLBALDH1A1
SCHEMBL4251552 0.86 RAB9A (0.46) RAB9AL3MBTL1KDM4EPOLBALDH1A1
SCHEMBL4249042 0.84 L3MBTL1 (0.47) RAB9AL3MBTL1POLBALDH1A1HTT
SCHEMBL4249037 0.84 L3MBTL1 (0.47) RAB9AL3MBTL1POLBALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL RAB9A 3116/4885L3MBTL1 3519/4885KDM4E 978/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL RAB9A 3116/4885L3MBTL1 3519/4885KDM4E 978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.