SCHEMBL4249053

SCHEMBL4249053

CCCOC(=O)/C=C(/Oc1ccccc1[N+](=O)[O-])C(=O)OCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.47
POLB P06746 2/20 0.44
NPC1 O15118 3/20 0.43
RECQL P46063 2/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
ALDH1A1 P00352 6/20 0.42
LMNA P02545 2/20 0.42
GLA P06280 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 5/20 0.42
MAPT P10636 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
MAPK1 P28482 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4249056 1.00 RAB9A (0.47) RAB9APOLBNPC1RECQLL3MBTL1
SCHEMBL4252616 1.00 RAB9A (0.47) RAB9APOLBNPC1RECQLL3MBTL1
SCHEMBL4251552 0.93 RAB9A (0.46) RAB9APOLBNPC1RECQLL3MBTL1
SCHEMBL4254610 0.93 RAB9A (0.46) RAB9APOLBNPC1RECQLL3MBTL1
SCHEMBL4251557 0.93 RAB9A (0.46) RAB9APOLBNPC1RECQLL3MBTL1
SCHEMBL4249037 0.91 L3MBTL1 (0.47) RAB9APOLBNPC1RECQLL3MBTL1
SCHEMBL4252634 0.91 L3MBTL1 (0.47) RAB9APOLBNPC1RECQLL3MBTL1
SCHEMBL4249042 0.91 L3MBTL1 (0.47) RAB9APOLBNPC1RECQLL3MBTL1
SCHEMBL4247741 0.88 RAB9A (0.58) RAB9APOLBNPC1RECQLL3MBTL1
SCHEMBL4247745 0.88 RAB9A (0.58) RAB9APOLBNPC1RECQLL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101497571-B Process for producing chromone compound SUMITOMO CO LTD 2012-07-04 CN disclosed
CN-1911896-B Process for producing benzopyrone compound SUMITOMO CHEMICAL CO 2010-09-15 CN disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
CN-101497571-A Process for producing chromone compound SUMITOMO CHEMICAL CO (JP) 2009-08-05 CN disclosed
CN-100509751-C Process for producing benzopyranone compound SUMITOMO CHEMICAL CO (JP) 2009-07-08 CN disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
CN-1911896-A Process for producing chromone compound SUMITOMO CHEMICAL CO (JP) 2007-02-14 CN disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
CN-1649824-A Process for producing benzopyranone compound SUMITOMO CHEMICAL CO (JP) 2005-08-03 CN disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL RAB9A 3116/4885POLB 2938/4885NPC1 2630/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL RAB9A 3116/4885POLB 2938/4885NPC1 2630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.