SCHEMBL4248630

SCHEMBL4248630

c1ccc(Oc2ccc3cc4ccccc4cc3c2Oc2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.44
KMT2A Q03164 1/20 0.44
NQO1 P15559 1/20 0.42
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
LTA4H P09960 1/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TTR P02766 3/20 0.39
GAA P10253 1/20 0.37
RCE1 Q9Y256 1/20 0.37
CTNNB1 P35222 1/20 0.37
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1052575 0.85 MAPT (0.52) MAPTKDM4EGLAKMT2ACYP1A2
SCHEMBL11578247 0.79 MAPT (0.44) MAPTKDM4EGLAKMT2ANQO1
SCHEMBL445495 0.79 CTNNB1 (0.44) MAPTKDM4EGLAKMT2ANQO1
SCHEMBL28627795 0.78 KDM4E (0.63) MAPTKDM4EGLAKMT2ACYP1A2
SCHEMBL1441005 0.77 CTNNB1 (0.43) MAPTKDM4EGLAKMT2ANQO1
SCHEMBL28554537 0.76 CYP1A2 (0.43) KDM4EKMT2ANQO1CYP1A2LTA4H
SCHEMBL9693024 0.76 LTA4H (0.46) MAPTKDM4EGLAKMT2ANQO1
SCHEMBL19205830 0.75 LTA4H (0.55) MAPTKDM4EGLAKMT2ACYP1A2
SCHEMBL9693541 0.74 GAA (0.49) MAPTKMT2ALTA4HTSHRALDH1A1
SCHEMBL25026524 0.73 NQO1 (0.41) MAPTKDM4EGLAKMT2ANQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009249307-A BIS(HYDROXYPHENYL)ANTHRACENE COMPOUND, AND METHOD OF PRODUCING THE SAME KRI INC 2009-10-29 JP disclosed
US-5084530-A Polyether ketone resins for molding materials and extrusion composites AMOCO CORPORATION (US) 1992-01-28 US disclosed
US-5037936-A Bis(acid chloride) terminated polyaryl ether ketone oligomer AMOCO CORPORATION (US) 1991-08-06 US disclosed
US-4968758-A MOLODING MATERIALS WITH EXCELLENT HEAT, SOLVENT, AND STRESS-CRACK RESISTANCE AMOCO CORPORATION (US) 1990-11-06 US disclosed
US-4959423-A IMPROVED CRYSTALLIZATION RATES AMOCO CORPORATION (US) 1990-09-25 US disclosed
US-4910289-A Crystal structure; blend with poly(arylene sulfide) AMOCO CORPORATION (US) 1990-03-20 US disclosed
US-4870153-A MELT PROCESSABILITY, MOLDING MATERIALS AMOCO CORPORATION (US) 1989-09-26 US disclosed
US-4861915-A Poly (aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1989-08-29 US disclosed
US-4786694-A Poly(aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1988-11-22 US disclosed