SCHEMBL28627795

SCHEMBL28627795

c1ccc(Oc2c3ccccc3cc3ccccc23)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.63
GLA P06280 2/20 0.63
KMT2A Q03164 2/20 0.63
MAPT P10636 1/20 0.63
KDM1A O60341 1/20 0.48
LTA4H P09960 4/20 0.48
TSHR P16473 1/20 0.48
GPR84 Q9NQS5 1/20 0.46
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C19 P33261 1/20 0.43
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24413984 0.88 GPR84 (0.52) KDM4EGLAKMT2AMAPTKDM1A
SCHEMBL28677270 0.86 KDM4E (0.49) KDM4EGLAKMT2AMAPTKDM1A
SCHEMBL2357775 0.85 GPR84 (0.52) KDM4EGLAKMT2AMAPTTSHR
SCHEMBL4898172 0.83 KDM4E (0.70) KDM4EGLAKMT2AMAPTKDM1A
SCHEMBL30003990 0.83 KDM4E (0.70) KDM4EGLAKMT2AMAPTKDM1A
SCHEMBL6246796 0.80 CYP1A2 (0.45) KDM4EGLAKMT2AMAPTKDM1A
SCHEMBL4248630 0.78 MAPT (0.44) KDM4EGLAKMT2AMAPTLTA4H
SCHEMBL455804 0.77 KDM4E (1.00) KDM4EGLAKMT2AMAPTKDM1A
SCHEMBL1052575 0.77 MAPT (0.52) KDM4EGLAKMT2AMAPTKDM1A
SCHEMBL676532 0.75 MAPT (0.50) KDM4EGLAKMT2AMAPTKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109627360-B Agglomerated propylene containing thermally reversible crosslinking group and preparation method thereof 江苏中煦聚烯烃研究院有限公司 2021-04-09 CN claimed
CN-109627360-B Agglomerated propylene containing thermally reversible crosslinking group and preparation method thereof 江苏中煦聚烯烃研究院有限公司 2021-04-09 CN disclosed