SCHEMBL1052575

SCHEMBL1052575

c1ccc(Oc2ccc3ccccc3c2Oc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
GLA P06280 1/20 0.52
KMT2A Q03164 1/20 0.52
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP2A6 P11509 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LTA4H P09960 1/20 0.42
KDM1A O60341 1/20 0.41
KCNA3 P22001 1/20 0.41
HPRT1 P00492 1/20 0.39
HPGD P15428 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19894095 0.87 MAPT (0.61) MAPTKDM4EGLAKMT2AALDH1A1
SCHEMBL7899099 0.85 KDM1A (0.56) MAPTKDM4EGLAKMT2ATSHR
SCHEMBL4248630 0.85 MAPT (0.44) MAPTKDM4EGLAKMT2ATSHR
SCHEMBL2284856 0.83 LTA4H (0.49) MAPTKDM4EGLAKMT2ATSHR
SCHEMBL30006655 0.81 GAA (0.49) MAPTKDM4EGLAKMT2ATSHR
SCHEMBL11894598 0.80 LMNA (0.54) MAPTKDM4ETSHRALDH1A1HSD17B10
SCHEMBL10590588 0.80 HTT (0.51) MAPTKDM4EALDH1A1HSD17B10TDP1
SCHEMBL9703810 0.79 HSPB1 (0.48) MAPTKDM4EKMT2AALDH1A1
SCHEMBL11578247 0.79 MAPT (0.44) MAPTKDM4EGLAKMT2AALDH1A1
SCHEMBL5992678 0.78 KDM4E (0.50) MAPTKDM4EGLAKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394176-B2 Polyimide gas separation membrane and gas separation method UBE INDUSTRIES, LTD. (JP) 2013-03-12 US claimed
US-20110000367-A1 POLYIMIDE GAS SEPARATION MEMBRANE AND GAS SEPARATION METHOD UBE INDUSSTRIES, LTD. (JP) 2011-01-06 US claimed
US-4716211-A 1,2-DICHLOROETHANE SOLVENT AMOCO CORPORATION (US) 1987-12-29 US claimed
US-4611033-A Process for stabilizing a poly(aryl ether ketone) UNION CARBIDE CORPORATION (US) 1986-09-09 US claimed
US-3953400-A Polyketones and methods therefor RAYCHEM CORPORATION (US) 1976-04-27 US claimed
US-8394176-B2 Polyimide gas separation membrane and gas separation method UBE INDUSTRIES, LTD. (JP) 2013-03-12 US disclosed
US-20110000367-A1 POLYIMIDE GAS SEPARATION MEMBRANE AND GAS SEPARATION METHOD UBE INDUSSTRIES, LTD. (JP) 2011-01-06 US disclosed
US-5886131-A Method for preparing 1,4-Bis(4-aminophenoxy)naphthalene and its polymers CHINA TEXTILE INSTITUTE (TW) 1999-03-23 US disclosed
US-5340904-A Polyimides, polyamides, polyamideimide copolymers; heat resistance, mechanical strength, high molecular weight NATIONAL SCIENCE COUNCIL (TW) 1994-08-23 US disclosed
US-5338881-A Process for preparing diketones EASTMAN CHEMICAL COMPANY (US) 1994-08-16 US disclosed
WO-1994005618-A1 PROCESS FOR THE PRODUCTION OF DIIODOKETONES EASTMAN KODAK COMPANY (US) 1994-03-17 WO disclosed
EP-0540653-A1 PROCESS FOR PREPARING DIKETONES AND KETO-ACIDS EASTMAN KODAK COMPANY (US) 1993-05-12 EP disclosed
EP-0221149-A1 BLOCK POLYMERS CONTAINING A POLY(ARYL ETHER KETONE) AND METHODS FOR THEIR PRODUCTION AMOCO CORPORATION (US) 1987-05-13 EP disclosed
WO-1986007598-A1 CHAIN-EXTENDED POLY (ARYL ETHER KETONES) AMOCO CORPORATION (US) 1986-12-31 WO disclosed
WO-1986006389-A1 BLOCK POLYMERS CONTAINING A POLY(ARYL ETHER KETONE) AND METHODS FOR THEIR PRODUCTION AMOCO CORPORATION (US) 1986-11-06 WO disclosed
US-4611033-A Process for stabilizing a poly(aryl ether ketone) UNION CARBIDE CORPORATION (US) 1986-09-09 US disclosed
EP-0189266-A2 Purification of haloacetyl derivatives of aromatic hydrocarbons THE DOW CHEMICAL COMPANY (US) 1986-07-30 EP disclosed
US-4229564-A SUITABLE FOR MELT PROCESSING AND EXTRUSION COATINGS RAYCHEM CORPORATION (US) 1980-10-21 US disclosed
US-4024314-A Electrical conductor insulated by a polyketones RAYCHEM CORPORATION (US) 1977-05-17 US disclosed
US-3953400-A Polyketones and methods therefor RAYCHEM CORPORATION (US) 1976-04-27 US disclosed