Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712349 | 0.73 | SIGMAR1 (0.54) | MAPK1SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL28312066 | 0.72 | ACHE (0.44) | MAPK1SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL4107014 | 0.70 | MAPK1 (0.57) | MAPK1SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL28285871 | 0.69 | MAPK1 (0.56) | MAPK1SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL1090206 | 0.68 | SIGMAR1 (0.65) | SIGMAR1ACHEKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL10293578 | 0.68 | SIGMAR1 (0.65) | SIGMAR1ACHEKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL1090204 | 0.68 | SIGMAR1 (0.65) | SIGMAR1ACHEKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL14695121 | 0.68 | GAA (0.49) | MAPK1SMN1; SMN2TSHRGAAALDH1A1 | |
| SCHEMBL31171617 | 0.68 | TSHR (0.43) | MAPK1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL31171531 | 0.68 | TSHR (0.43) | MAPK1MEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363705-A4 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1363705-A1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002062423-A1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-15 | — | — | WO | disclosed |