SCHEMBL4249239

SCHEMBL4249239

C=CS(=O)(=O)c1ccccc1N.O=S(=O)(O)c1cccc2cccc(Nc3ccccc3)c12

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.72
MAPK14 Q16539 2/20 0.72
FABP4 P15090 1/20 0.72
CCNA2 P20248 1/20 0.72
CDK2 P24941 1/20 0.72
NR4A1 P22736 1/20 0.70
SNCA P37840 2/20 0.51
CHAT P28329 1/20 0.51
FABP1 P07148 1/20 0.48
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 3/20 0.45
GAA P10253 3/20 0.45
MAPT P10636 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
NSD2 O96028 1/20 0.45
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
APOBEC3A P31941 1/20 0.45
RECQL P46063 1/20 0.45
CASP6 P55212 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43158 0.85 FABP4 (1.00) TTRMAPK14FABP4CCNA2CDK2
SCHEMBL29381891 0.85 FABP4 (1.00) TTRMAPK14FABP4CCNA2CDK2
Questiomycin B SCHEMBL20817145 0.84 TTR (0.78) TTRMAPK14FABP4CCNA2CDK2
SCHEMBL1786500 0.84 FABP4 (0.97) TTRMAPK14FABP4CCNA2CDK2
SCHEMBL10353163 0.84 FABP4 (0.97) TTRMAPK14FABP4CCNA2CDK2
Ammonia Solution, Strong SCHEMBL592280 0.84 NR4A1 (1.00) TTRMAPK14FABP4CCNA2CDK2
Ammonia Solution, Strong SCHEMBL592279 0.84 NR4A1 (1.00) TTRMAPK14FABP4CCNA2CDK2
SCHEMBL6654772 0.84 FABP4 (0.97) TTRMAPK14FABP4CCNA2CDK2
Ammonia Solution, Strong SCHEMBL31666356 0.82 NR4A1 (0.97) TTRMAPK14FABP4CCNA2CDK2
SCHEMBL7522280 0.78 FABP4 (0.84) TTRMAPK14FABP4CCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10302591-B2 Sharply resolving labeled protein molecular weight standards Life Technologies Corporation (US) 2019-05-28 US disclosed
US-20180031522-A1 SHARPLY RESOLVING LABELED PROTEIN MOLECULAR WEIGHT STANDARDS INVITROGEN CORPORATION 2018-02-01 US disclosed
US-9733212-B2 Sharply resolving labeled protein molecular weight standards Life Technologies Corporation (US) 2017-08-15 US disclosed
US-20130207044-A1 Sharply Resolving Labeled Protein Molecular Weight Standards Life Technologies Corporation (US) 2013-08-15 US disclosed
US-20090178926-A1 Sharply Resolving Labeled Protein Molecular Weight Standards INVITROGEN CORPORATION (US) 2009-07-16 US disclosed
EP-2069386-A2 SHARPLY RESOLVING LABELED PROTEIN MOLECULAR WEIGHT STANDARDS Life Technologies Corporation (US) 2009-06-17 EP disclosed
US-20090087873-A1 SHARPLY RESOLVING LABELED PROTEIN MOLECULAR WEIGHT STANDARDS INVITROGEN CORPORATION (US) 2009-04-02 US disclosed
WO-2008042495-A2 SHARPLY RESOLVING LABELED PROTEIN MOLECULAR WEIGHT STANDARDS Life Technologies Corporation (US) 2008-04-10 WO disclosed