Chloroform

Chloroform

SCHEMBL4249292

CCCCCCC(Cl)(Cl)Cl.ClC(Cl)Cl

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
THRB P10828 1/20 0.42
FDPS P14324 10/20 0.40
SMPD1 P17405 2/20 0.40
ALDH1A1 P00352 1/20 0.39
GGPS1 O95749 6/20 0.38
DNM1 Q05193 1/20 0.36
CES2 O00748 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL14672693 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL14672704 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL4592445 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL14735852 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL3257950 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL459208 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL14672707 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL19469979 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL1493337 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL1724110 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084171-B1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE SHOWA DENKO KK (JP) 2013-04-10 EP disclosed
US-20090315454-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE SHOWA DENKO K.K. (JP) 2009-12-24 US disclosed
EP-2084171-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE Showa Denko K.K. (JP) 2009-08-05 EP disclosed
WO-2008056799-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE SHOWA DENKO K.K. (JP) 2008-05-15 WO disclosed
US-20080050604-A1 Polymer Light-Emitting Material and Organic Light Emitting Element SHOWA DENKO K.K. (JP) 2008-02-28 US disclosed
US-6835471-B2 Discotic liquid crystal compounds using a multifunction porphyrin derivative compound which is light-emissive and especially has phosphorescent light emission properties and liquid crystal properties simultaneously CANON KABUSHIKI KAISHA (JP) 2004-12-28 US disclosed
US-20030034722-A1 Light emitting device and display unit which make use of porphyrin derivative compound CANON KABUSHIKI KAISHA (JP) 2003-02-20 US disclosed
US-6150363-A INHIBITORY AGENT OF GLUTAMIC ACID TOXICITY WHICH CONTAINS A DIHYDROPHENAZINECARBOXYLIC ACID DERIVATIVES NIPPON CHEMIPHAR CO., LTD. (JP) 2000-11-21 US disclosed
EP-0945444-A1 DIHYDROPHENAZINECARBOXYLIC ACID DERIVATIVES NIPPON CHEMIPHAR CO., LTD. (JP) 1999-09-29 EP disclosed
US-5834575-A POLYIMIDE OR POLYACRYLATE WITH PENDANT GROUP CONTAINING THIOPHENE RING, BENZENE RING AND VICINAL NITRILE GROUPS, SWITCHES FOR OPTICAL SIGNALS, COMMUNICATION TECHNOLOGY HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-11-10 US disclosed
US-5308848-A Side effect reduction MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-05-03 US disclosed
EP-0452107-A1 Pyrimidinedione derivatives and antiarrythmic agents containing same MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-10-16 EP disclosed
US-4916058-A CHROMOGENS KYOWA MEDEX CO., LTD. (JP) 1990-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090315454-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE ELP1, RUVBL1, LIG1 TSHR 1790/4885THRB 4315/4885FDPS 3581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.