Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 10/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL14672693 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Chloroform SCHEMBL14672704 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Chloroform SCHEMBL4592445 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Chloroform SCHEMBL14735852 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Chloroform SCHEMBL3257950 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Chloroform SCHEMBL14672707 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Chloroform SCHEMBL19469979 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Chloroform SCHEMBL4249292 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Chloroform SCHEMBL1493337 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| Chloroform SCHEMBL1724110 | 1.00 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364223-B2 | Organic compound, electrochromic element, optical filter, lens unit, image pickup apparatus, and window member | CANON KABUSHIKI KAISHA (JP) | 2019-07-30 | — | — | US | disclosed |
| US-20180237393-A1 | ORGANIC COMPOUND, ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGE PICKUP APPARATUS, AND WINDOW MEMBER | CANON KABUSHIKI KAISHA (JP) | 2018-08-23 | — | — | US | disclosed |
| US-20160091505-A1 | Molecular Template and Manufacturing Method Therefor | HITACHI, LTD. (JP) | 2016-03-31 | — | — | US | disclosed |
| US-20140227798-A1 | Molecular Template and Method for Producing Same | HITACHI, LTD. (JP) | 2014-08-14 | — | — | US | disclosed |
| EP-2762884-A1 | MOLECULAR TEMPLATE AND METHOD FOR PRODUCING SAME | Hitachi, Ltd. (JP) | 2014-08-06 | — | — | EP | disclosed |
| CN-103688172-A | Molecular template and method for producing same | HITACHI LTD | 2014-03-26 | — | — | CN | disclosed |
| US-8609847-B2 | Dihydroquinolinone derivatives | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2013-12-17 | — | — | US | disclosed |
| EP-2393802-B1 | DIHYDROQUINOLINONE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-20120116073-A1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR COL, LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
| US-20120022064-A1 | DIHYDROQUINOLINONE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
| CN-102307867-A | Dihydroquinolinone derivatives | TAISHO PHARMACEUTICAL CO LTD | 2012-01-04 | — | — | CN | disclosed |
| EP-2393802-A1 | DIHYDROQUINOLINONE DERIVATIVES | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010090347-A1 | DIHYDROQUINOLINONE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-08-12 | — | — | WO | disclosed |
| EP-2058304-A1 | P2X4 RECEPTOR ANTAGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-20070021418-A1 | Method of inhibiting production of osteopontin | KOWA CO., LTD. (JP) | 2007-01-25 | — | — | US | disclosed |
| EP-1650195-A1 | METHOD OF INHIBITING PRODUCTION OF OSTEOPONTIN | Kowa Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022064-A1 | DIHYDROQUINOLINONE DERIVATIVES | PER2, CRY1, BACE1 | TSHR 3287/4885THRB 1276/4885FDPS 2660/4885 |
| US-20180237393-A1 | ORGANIC COMPOUND, ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGE PICKUP APPARATUS, AND WINDOW MEMBER | EML4, AP2M1, AP2A2 | TSHR 3575/4885THRB 3531/4885FDPS 4254/4885 |
| US-20070021418-A1 | Method of inhibiting production of osteopontin | HDGF, PGF, FGF23 | TSHR 653/4885THRB 438/4885FDPS 2292/4885 |
| US-10364223-B2 | Organic compound, electrochromic element, optical filter, lens unit, image pickup apparatus, and window member | EML4, AP2M1, AP2A2 | TSHR 3575/4885THRB 3531/4885FDPS 4254/4885 |
| US-20120116073-A1 | P2X4 RECEPTOR ANTAGONIST | P2RX1, P2RX3, P2RX4 | TSHR 482/4885THRB 591/4885FDPS 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.