Chloroform

Chloroform

SCHEMBL1724110

CCCCCCC(Cl)(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
THRB P10828 1/20 0.42
FDPS P14324 10/20 0.40
SMPD1 P17405 2/20 0.40
ALDH1A1 P00352 1/20 0.39
GGPS1 O95749 6/20 0.38
DNM1 Q05193 1/20 0.36
CES2 O00748 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL14672693 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL14672704 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL4592445 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL14735852 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL3257950 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL459208 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL14672707 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL19469979 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL4249292 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1
Chloroform SCHEMBL1493337 1.00 TSHR (0.42) TSHRTHRBFDPSSMPD1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114752227-B Sensitizing dye, sensitizing dye composition for photoelectric conversion, photoelectric conversion element using same, and dye sensitized solar cell 保土谷化学工业株式会社 2023-09-01 CN disclosed
CN-114752227-A Sensitizing dye, sensitizing dye composition for photoelectric conversion, photoelectric conversion element using same, and dye-sensitized solar cell 保土谷化学工业株式会社 2022-07-15 CN disclosed
CN-110337466-B Sensitizing dye, sensitizing dye composition for photoelectric conversion, photoelectric conversion element using same, and dye-sensitized solar cell 保土谷化学工业株式会社 2022-03-08 CN disclosed
CN-110337466-A Sensitizing dye, sensitizing dye composition for photoelectric conversion, photoelectric conversion element using same, and dye-sensitized solar cell 保土谷化学工业株式会社 2019-10-15 CN disclosed
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2019-07-18 US disclosed
US-20120116073-A1 P2X4 RECEPTOR ANTAGONIST NIPPON CHEMIPHAR COL, LTD. (JP) 2012-05-10 US disclosed
EP-1753839-B1 POLYMER LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT SHOWA DENKO KK (JP) 2011-07-20 EP disclosed
US-20100256123-A1 P2X4 RECEPTOR ANTAGONIST NIPPON CHEMIPHAR CO., LTD. (JP) 2010-10-07 US disclosed
CN-101541768-A P2X4Receptor antagonists NIPPON CHEMIPHAR CO (JP) 2009-09-23 CN disclosed
EP-2058304-A1 P2X4 RECEPTOR ANTAGONIST Nippon Chemiphar Co., Ltd. (JP) 2009-05-13 EP disclosed
US-7196081-B2 Compounds with hydroxycarbonyl-halogenoalkyl side chains CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-03-27 US disclosed
US-20050192449-A1 Compounds with hydroxycarbonyl-halogenoalkyl side chains CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2005-09-01 US disclosed
US-6737417-B2 AN ANTIESTROGENIC AGENT CONTAININING AROMATIC OR HETEROAROMATIC COMPOUNDS CONTAINING HYDROXYCARBONYL OR METAL SALT- HALOGENOALKYL SIDE CHAIN; USEFUL FOR TREATING BREAST CANCER CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2004-05-18 US disclosed
EP-1361205-A1 Compounds with hydroxycarbonyl-halogenalkyl side chains CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-11-12 EP disclosed
US-20030130347-A1 Compounds with hydroxycarbonyl-halogenoalkyl side chains CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-07-10 US disclosed
US-20030114524-A1 Compounds with hydroxycarbonyl-halogenoalkyl side chain CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-06-19 US disclosed
EP-1241158-A1 COMPOUND HAVING HYDROXYCARBONYL-HALOGENOALKYL SIDE CHAIN CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2002-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256123-A1 P2X4 RECEPTOR ANTAGONIST P2RX1, P2RX3, P2RX4 TSHR 482/4885THRB 591/4885FDPS 4562/4885
US-20050192449-A1 Compounds with hydroxycarbonyl-halogenoalkyl side chains CYP19A1, HSD17B11, SHBG TSHR 1465/4885THRB 1372/4885FDPS 2882/4885
US-20120116073-A1 P2X4 RECEPTOR ANTAGONIST P2RX1, P2RX3, P2RX4 TSHR 482/4885THRB 591/4885FDPS 4562/4885
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT SLC43A1, SLC7A5, SLC39A3 TSHR 2938/4885THRB 3671/4885FDPS 4603/4885
US-20030114524-A1 Compounds with hydroxycarbonyl-halogenoalkyl side chain HSD17B11, CYP19A1, SHBG TSHR 2231/4885THRB 1257/4885FDPS 3181/4885
US-20030130347-A1 Compounds with hydroxycarbonyl-halogenoalkyl side chains HSD17B11, CYP19A1, SHBG TSHR 2277/4885THRB 1309/4885FDPS 3232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.