SCHEMBL42501

SCHEMBL42501

NC1CCN(Cc2ccccc2)C1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 9/20 0.58
BCHE P06276 8/20 0.57
BACE1 P56817 8/20 0.57
LTA4H P09960 1/20 0.56
CCR3 P51677 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56
ALDH1A1 P00352 1/20 0.56
SIGMAR1 Q99720 2/20 0.55
DRD2 P14416 1/20 0.53
DRD4 P21917 1/20 0.53
DRD3 P35462 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL239922 1.00 ACHE (0.58) ACHEBCHEBACE1LTA4HCCR3
SCHEMBL330609 1.00 ACHE (0.58) ACHEBCHEBACE1LTA4HCCR3
SCHEMBL14793661 1.00 ACHE (0.58) ACHEBCHEBACE1LTA4HCCR3
Bromide SCHEMBL2495449 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Hydrochloric Acid SCHEMBL697482 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Hydrochloric Acid SCHEMBL2905438 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Hydrochloric Acid SCHEMBL20183286 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Bromide SCHEMBL2899465 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Acetic Acid SCHEMBL2500600 0.91 ACHE (0.53) ACHELTA4HALDH1A1SIGMAR1DRD2
Acetic Acid SCHEMBL2904677 0.91 ACHE (0.53) ACHELTA4HALDH1A1SIGMAR1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025122121-A2 COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND THE METHOD OF OBTAINING THESE COMPOUNDS HACETTEPE UNIVERSITESI REKTORLUK (TR) 2025-06-12 WO claimed
CN-114369052-B Synthesis method of 3-aminopyrrolidine dihydrochloride 赤峰万泽药业股份有限公司 2024-10-15 CN claimed
CN-111718250-B Method for preparing R-citronellal 万华化学集团股份有限公司 2022-04-22 CN claimed
CN-114369052-A Synthetic method of 3-aminopyrrolidine dihydrochloride 赤峰万泽药业股份有限公司 2022-04-19 CN claimed
EP-3912973-A2 SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE Dana-Farber Cancer Institute, Inc. (US) 2021-11-24 EP claimed
CN-111718250-A Method for preparing R-citronellal 万华化学集团股份有限公司 2020-09-29 CN claimed
CN-111620802-A Preparation method of cefditoren intermediate (R) -1-benzyl-3-aminopyrrolidine 山西千岫制药有限公司 2020-09-04 CN claimed
EP-2957575-B1 OPTICALLY ACTIVE POLY(DIPHENYLACETYLENE) COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AS OPTICAL ISOMER SEPARATING AGENT NAT UNIV CORP KANAZAWA UNIV (JP) 2017-10-18 EP claimed
EP-2623593-B1 NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE KANEKA CORP (JP) 2017-07-12 EP claimed
EP-2684953-B1 MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME KANEKA CORP (JP) 2017-06-28 EP claimed
EP-0638068-B1 PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES WARNER LAMBERT CO (US) 1999-06-23 EP claimed
EP-0638068-A1 PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES WARNER-LAMBERT COMPANY (US) 1995-02-15 EP claimed
WO-1993022283-A1 PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES WARNER-LAMBERT COMPANY (US) 1993-11-11 WO claimed
US-5177217-A Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines WARNER-LAMBERT COMPANY (US) 1993-01-05 US claimed
EP-0310854-B1 PROCESS FOR THE MANUFACTURE OF 3-AMINO-1-BENZYL-PYRROLIDINES BAYER AG (DE) 1992-05-20 EP claimed
US-4995997-A Containing aromatic amine YUSHIRO CHEMICAL INDUSTRY CO., LTD. (JP) 1991-02-26 US claimed
EP-0391169-A2 Enantiomeric pure 7-(3-amino-1-pyrrolidinyl)-chinolon-and-naphthyridon carboxylic acids BAYER AG (DE) 1990-10-10 EP claimed
EP-0388320-A1 Antibacterial water-soluble cutting fluids resistant to yeast-like fungi YUSHIRO CHEMICAL INDUSTRY CO. LTD. (JP) 1990-09-19 EP claimed
US-4910319-A Process for preparing 3-amino-1-benzylpyrrolidines BAYER AKTIENGESELLSCHAFT (DE) 1990-03-20 US claimed
EP-0310854-A1 Process for the manufacture of 3-amino-1-benzyl-pyrrolidines BAYER AG (DE) 1989-04-12 EP claimed