SCHEMBL330609

SCHEMBL330609

N[C@H]1CCN(Cc2ccccc2)C1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 9/20 0.58
BCHE P06276 8/20 0.57
BACE1 P56817 8/20 0.57
LTA4H P09960 1/20 0.56
CCR3 P51677 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56
ALDH1A1 P00352 1/20 0.56
SIGMAR1 Q99720 2/20 0.55
DRD2 P14416 1/20 0.53
DRD4 P21917 1/20 0.53
DRD3 P35462 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL239922 1.00 ACHE (0.58) ACHEBCHEBACE1LTA4HCCR3
SCHEMBL42501 1.00 ACHE (0.58) ACHEBCHEBACE1LTA4HCCR3
SCHEMBL14793661 1.00 ACHE (0.58) ACHEBCHEBACE1LTA4HCCR3
Bromide SCHEMBL2495449 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Hydrochloric Acid SCHEMBL697482 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Hydrochloric Acid SCHEMBL2905438 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Hydrochloric Acid SCHEMBL20183286 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Bromide SCHEMBL2899465 0.98 ACHE (0.56) ACHEBCHEBACE1LTA4HCCR3
Acetic Acid SCHEMBL2500600 0.91 ACHE (0.53) ACHELTA4HALDH1A1SIGMAR1DRD2
Acetic Acid SCHEMBL2904677 0.91 ACHE (0.53) ACHELTA4HALDH1A1SIGMAR1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598504-A2 MICROPARTICLE AND IMPLANT FORMULATIONS FOR CGMP ANALOG THERAPY Mireca Medicines GmbH (DE) 2025-08-13 EP claimed
WO-2024074585-A2 MICROPARTICLE AND IMPLANT FORMULATIONS FOR cGMP ANALOG THERAPY MIRECA MEDICINES GMBH (DE) 2024-04-11 WO claimed
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2023-08-03 US claimed
EP-2623593-B1 NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE KANEKA CORP (JP) 2017-07-12 EP claimed
EP-2623595-B1 NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF KANEKA CORP (JP) 2016-11-02 EP claimed
US-9481871-B2 Nucleic acid encoding a polpeptide having aminotransferase activity, vectors and host cells comprising the nucleic acid KANEKA CORPORATION (JP) 2016-11-01 US claimed
US-9481870-B2 Nucleic acid encoding a polypeptide having aminotransferase activity, vectors and host cells comprising the nucleic acid KANEKA CORPORATION (JP) 2016-11-01 US claimed
CN-102603592-B Preparation method for (R)-1-benzyl-3-aminopyrrolidine and (S)-1-benzyl-3-aminopyrrolidine SHANGHAI INST TECHNOLOGY 2014-08-20 CN claimed
CN-103534350-A Novel aminotransferase exhibiting high activity for glutamic acid, gene encoding the same, and method for using the same KANEKA CORP 2014-01-22 CN claimed
US-20130210092-A1 Novel Transaminase, Gene Encoding the Same, and Method Using Them KANEKA CORPORATION (JP) 2013-08-15 US claimed
US-20060281733-A1 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carvoxylic acid amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases ELAN PHARMACEUTICALS, INC. 2006-12-14 US claimed
EP-1633348-A1 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES Elan Pharmaceuticals, Inc. (US) 2006-03-15 EP claimed
US-20050020659-A1 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists ELAN PHARMACEUTICALS, INC. 2005-01-27 US claimed
WO-2004098589-A1 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES ELAN PHARMACEUTICALS, INC. (US) 2004-11-18 WO claimed
JP-3264928-B2 2002-03-11 JP claimed
EP-0638068-B1 PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES WARNER LAMBERT CO (US) 1999-06-23 EP claimed
EP-0638068-A1 PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES WARNER-LAMBERT COMPANY (US) 1995-02-15 EP claimed
WO-1993022283-A1 PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES WARNER-LAMBERT COMPANY (US) 1993-11-11 WO claimed
US-5177217-A Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines WARNER-LAMBERT COMPANY (US) 1993-01-05 US claimed
EP-0391169-A2 Enantiomeric pure 7-(3-amino-1-pyrrolidinyl)-chinolon-and-naphthyridon carboxylic acids BAYER AG (DE) 1990-10-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES PRKG1, PRKG2, PRKAG3 ACHE 3513/4885BCHE 3091/4885BACE1 4477/4885
US-20050020659-A1 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists BDKRB1, BDKRB2, BRS3 ACHE 2842/4885BCHE 1083/4885BACE1 724/4885
US-20060281733-A1 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carvoxylic acid amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases BDKRB1, BDKRB2, CNR1 ACHE 3424/4885BCHE 1045/4885BACE1 1314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.