Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250470 | 1.00 | GNRHR (0.39) | GNRHRBRD4KIF11MALT1IDO1 | |
| SCHEMBL4252319 | 0.95 | BRD4 (0.39) | GNRHRBRD4KIF11NPSR1L3MBTL1 | |
| SCHEMBL4248792 | 0.95 | GNRHR (0.38) | GNRHRBRD4KIF11IDO1NPSR1 | |
| SCHEMBL4248789 | 0.95 | GNRHR (0.38) | GNRHRBRD4KIF11IDO1NPSR1 | |
| SCHEMBL4252323 | 0.95 | BRD4 (0.39) | GNRHRBRD4KIF11NPSR1L3MBTL1 | |
| SCHEMBL4250123 | 0.88 | KIF11 (0.39) | GNRHRBRD4KIF11HPGDHTT | |
| SCHEMBL4250128 | 0.88 | KIF11 (0.39) | GNRHRBRD4KIF11HPGDHTT | |
| SCHEMBL4247238 | 0.86 | GNRHR (0.40) | GNRHRBRD4KIF11IDO1ALDH1A1 | |
| SCHEMBL4247240 | 0.86 | GNRHR (0.40) | GNRHRBRD4KIF11IDO1ALDH1A1 | |
| SCHEMBL4054984 | 0.85 | KIF11 (0.39) | GNRHRBRD4KIF11MALT1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035426-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007144384-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2007-12-21 | — | — | WO | disclosed |