SCHEMBL425101

SCHEMBL425101

O=C(NNc1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 1.00
GAA P10253 6/20 0.68
ALDH1A1 P00352 6/20 0.68
KDM4E B2RXH2 3/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
MAPT P10636 3/20 0.62
MEN1 O00255 1/20 0.62
MAPK1 P28482 1/20 0.62
GFER P55789 1/20 0.62
KMT2A Q03164 1/20 0.62
CYP3A4 P08684 1/20 0.59
ALOX5 P09917 1/20 0.59
TSHR P16473 1/20 0.59
POLB P06746 2/20 0.59
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
CTDSP1 Q9GZU7 2/20 0.57
HPGD P15428 1/20 0.57
ALOX12 P18054 1/20 0.57
KCNK3 O14649 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9017504 0.98 PTGS2 (0.96) PTGS2GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL9785877 0.90 PTGS2 (0.81) PTGS2GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL10906039 0.89 PTGS2 (0.79) PTGS2GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL8420633 0.88 PTGS2 (0.78) PTGS2GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL11142311 0.86 PTGS2 (0.75) PTGS2GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL11783307 0.86 PTGS2 (0.86) PTGS2GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL6898441 0.86 PTGS2 (1.00) PTGS2GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL250413 0.86 PTGS2 (0.75) PTGS2GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL4897180 0.86 PTGS2 (0.75) PTGS2GAAALDH1A1KDM4ESMN1; SMN2
SCHEMBL7040726 0.86 PTGS2 (1.00) PTGS2GAAALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118731248-A Establishment method and application of reference GC-MS fingerprint of Juanbi decoction substance 广西中医药大学百年乐制药有限公司 2024-10-01 CN claimed
US-7115676-B2 Adhesive compositions for bonding passive substrates HENKEL CORPORATION (US) 2006-10-03 US claimed
US-6689738-B2 ANTISOILANTS, BLEACHING UNILEVER HOME AND PERSONAL CARE USA DIVISION OF CONOPCO, INC. 2004-02-10 US claimed
US-20030217808-A1 Adhesive compositions for bonding passive substrates Henkel IP & Holding GmbH (DE) 2003-11-27 US claimed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP claimed
US-20020119900-A1 Oxidation process and composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-08-29 US claimed
US-6384007-B1 INTENSIFERS FOR OXIDATION OF PHENOL WITH ENZYMES AND HYDRAZINE COMPOUNDS UNILEVER HOME & PERSONAL USA DIVISION OF CONOPCO, INC. 2002-05-07 US claimed
US-20020016279-A1 Enzymatic oxidation composition and process UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-02-07 US claimed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO claimed
EP-0357082-B1 Silver halide photographic emulsions FUJI PHOTO FILM CO LTD (JP) 1996-12-11 EP claimed
US-4971889-A Spectral sensitizing dye containnig a hydrazine residue FUJI PHOTO FILM CO., LTD. (JP) 1990-11-20 US claimed
EP-0357082-A2 Silver halide photographic emulsions FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP claimed
US-4138570-A METHINE DYE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-06 US claimed
CN-119431397-B Benzotriazine free radical compound, preparation method thereof and application thereof in organic memristors and artificial synapses ZHENGZHOU UNIVERSITY (CN) 2026-05-26 CN disclosed
US-20260109883-A1 ANAEROBIC ADHESIVE COMPOSITION OKURA INDUSTRIAL CO LTD (JP) 2026-04-23 US disclosed
EP-4714992-A1 POLYTETRAMETHYLENE GLYCOL-BASED (METH)ACRYLATE COMPOUND Cemedine Co., Ltd. (JP) 2026-03-25 EP disclosed
US-4035144-A Dyeing preparations containing boric acid for preparing water-insoluble azo dyestuffs on fiber HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed
US-3965087-A Trisazo dye containing a diphenylenesulfone structure SAKAI CHEMICAL INDUSTRY COMPANY LTD. (JA) 1976-06-22 US disclosed
US-3963728-A ACYLATION OF NITROGEN CONTAINING COMPOUNDS USING ESTERS KYOWA HAKKO KOGYO CO., LTD. (JA) 1976-06-15 US disclosed
US-3951941-A POLYAZODYE SAKAI CHEMICAL INDUSTRY COMPANY, LIMITED (JA) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109883-A1 ANAEROBIC ADHESIVE COMPOSITION MAT2B, MAT1A, MMAB PTGS2 1131/4885GAA 3940/4885ALDH1A1 513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.