SCHEMBL6898441

SCHEMBL6898441

Cc1ccc(NNC(=O)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 7/20 1.00
SMN1; SMN2 Q16637 3/20 0.68
MAPT P10636 3/20 0.68
NPC1 O15118 1/20 0.68
RAB9A P51151 1/20 0.68
GAA P10253 4/20 0.61
ALDH1A1 P00352 3/20 0.59
KDM4E B2RXH2 2/20 0.58
CCR6 P51684 1/20 0.57
MAPK1 P28482 2/20 0.56
USP2 O75604 1/20 0.56
MCL1 Q07820 1/20 0.56
POLB P06746 2/20 0.56
LMNA P02545 1/20 0.56
MEN1 O00255 1/20 0.54
GFER P55789 1/20 0.54
KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11783307 0.93 PTGS2 (0.86) PTGS2SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL7082949 0.89 PTGS2 (0.79) PTGS2SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL425101 0.86 PTGS2 (1.00) PTGS2SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL11684414 0.85 PTGS2 (0.72) PTGS2SMN1; SMN2MAPTNPC1RAB9A
Hydrochloric Acid SCHEMBL9017504 0.84 PTGS2 (0.96) PTGS2SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL5166735 0.84 ALDH1A1 (0.83) PTGS2SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL5613011 0.84 PTGS2 (0.72) PTGS2SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL8420633 0.83 PTGS2 (0.78) PTGS2SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL28871751 0.82 PTGS2 (0.70) PTGS2NPC1RAB9AGAAALDH1A1
SCHEMBL7821761 0.82 ALDH1A1 (0.71) PTGS2MAPTGAAALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689738-B2 ANTISOILANTS, BLEACHING UNILEVER HOME AND PERSONAL CARE USA DIVISION OF CONOPCO, INC. 2004-02-10 US claimed
EP-1330507-A1 OXIDATION PROCESS AND COMPOSITION UNILEVER PLC (GB) 2003-07-30 EP claimed
US-20020119900-A1 Oxidation process and composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-08-29 US claimed
WO-2002036724-A1 OXIDATION PROCESS AND COMPOSITION UNILEVER N.V. (NL) 2002-05-10 WO claimed
US-20020016279-A1 Enzymatic oxidation composition and process UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-02-07 US claimed
EP-3444337-B1 METHOD OF CLEANING PROCTER & GAMBLE (US) 2024-12-18 EP disclosed
EP-3444336-B1 CLEANING AGENT PROCTER & GAMBLE (US) 2024-05-08 EP disclosed
US-20210147765-A9 CLEANING KIT THE PROCTER AND GAMBLE COMPANY 2021-05-20 US disclosed
US-20210071117-A9 CLEANING AGENT THE PROCTER AND GAMBLE COMPANY 2021-03-11 US disclosed
CN-110892065-A Cleaning method 宝洁公司 2020-03-17 CN disclosed
US-20200063073-A1 METHOD OF CLEANING THE PROCTER AND GAMBLE COMPANY 2020-02-27 US disclosed
US-20200063071-A1 CLEANING AGENT PROCTER & GAMBLE (US) 2020-02-27 US disclosed
US-20200063072-A1 CLEANING KIT PROCTER & GAMBLE (US) 2020-02-27 US disclosed
EP-3444323-A1 CLEANING KIT The Procter & Gamble Company (US) 2019-02-20 EP disclosed
EP-3444336-A1 CLEANING AGENT The Procter & Gamble Company (US) 2019-02-20 EP disclosed
EP-3444337-A1 METHOD OF CLEANING The Procter & Gamble Company (US) 2019-02-20 EP disclosed
US-6689738-B2 ANTISOILANTS, BLEACHING UNILEVER HOME AND PERSONAL CARE USA DIVISION OF CONOPCO, INC. 2004-02-10 US disclosed
US-20020119900-A1 Oxidation process and composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-08-29 US disclosed
US-20020016279-A1 Enzymatic oxidation composition and process UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-02-07 US disclosed
WO-2001092454-A1 ENZYMATIC OXIDATION COMPOSITION AND PROCESS UNILEVER N.V. (NL) 2001-12-06 WO disclosed