Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.50 |
| ▸ | LIPC | P11150 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 10/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | LPL | P06858 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956496 | 0.88 | PDE3B (0.51) | ACACBFPR2PROKR1 | |
| SCHEMBL23636616 | 0.85 | LIPG (0.51) | LIPGLIPCACACBNOTUM | |
| SCHEMBL7947314 | 0.85 | ACACB (0.46) | ACACB | |
| SCHEMBL7956152 | 0.85 | ACACB (0.52) | ACACB | |
| SCHEMBL7961497 | 0.84 | LIPG (0.60) | LIPGNOTUMSCDCYP3A4 | |
| SCHEMBL7956524 | 0.84 | LIPG (0.60) | LIPGNOTUMSCDCYP3A4 | |
| SCHEMBL7956252 | 0.84 | LIPG (0.60) | LIPGNOTUMSCDCYP3A4 | |
| SCHEMBL7956662 | 0.83 | ACACB (0.55) | ACACB | |
| SCHEMBL7956861 | 0.83 | ACACB (0.51) | ACACB | |
| SCHEMBL23632330 | 0.82 | HRH3 (0.54) | LIPGLIPCACACBNOTUMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |