Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13276650 | 1.00 | NPC1 (0.56) | NPC1RAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL13276651 | 1.00 | NPC1 (0.56) | NPC1RAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL4252476 | 1.00 | NPC1 (0.56) | NPC1RAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL4257860 | 0.79 | RAB9A (0.47) | NPC1RAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL4257866 | 0.79 | RAB9A (0.47) | NPC1RAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL4258810 | 0.78 | L3MBTL1 (0.43) | NPC1RAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL4258797 | 0.78 | L3MBTL1 (0.43) | NPC1RAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL4258791 | 0.78 | L3MBTL1 (0.43) | NPC1RAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL4249760 | 0.75 | L3MBTL1 (0.43) | NPC1RAB9AALDH1A1CYP1A2HPGD | |
| SCHEMBL4249749 | 0.75 | L3MBTL1 (0.43) | NPC1RAB9AALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | claimed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | claimed |
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |