Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257860 | 1.00 | RAB9A (0.47) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL4252476 | 0.79 | NPC1 (0.56) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL13276651 | 0.79 | NPC1 (0.56) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL13276650 | 0.79 | NPC1 (0.56) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL4252477 | 0.79 | NPC1 (0.56) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL4249749 | 0.74 | L3MBTL1 (0.43) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL4249755 | 0.74 | L3MBTL1 (0.43) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL4249760 | 0.74 | L3MBTL1 (0.43) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL4258797 | 0.74 | L3MBTL1 (0.43) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL4258791 | 0.74 | L3MBTL1 (0.43) | RAB9ASMN1; SMN2ALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | claimed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | claimed |
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |