Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252583 | 1.00 | GPR35 (0.56) | GPR35TSHRTDP1ALDH1A1ALPL | |
| SCHEMBL30893562 | 0.85 | TSHR (0.68) | GPR35TSHRTDP1ALDH1A1GAA | |
| SCHEMBL3671 | 0.85 | TSHR (0.68) | GPR35TSHRTDP1ALDH1A1GAA | |
| SCHEMBL8510920 | 0.84 | GPR35 (0.55) | GPR35TSHRTDP1ALDH1A1ALPL | |
| Lithium Ion SCHEMBL7791976 | 0.83 | TSHR (0.66) | GPR35TSHRTDP1ALDH1A1GAA | |
| SCHEMBL16267318 | 0.83 | TSHR (0.66) | GPR35TSHRTDP1ALDH1A1GAA | |
| SCHEMBL10824707 | 0.83 | TSHR (0.66) | GPR35TSHRTDP1ALDH1A1GAA | |
| SCHEMBL28208709 | 0.83 | TSHR (0.66) | GPR35TSHRTDP1ALDH1A1GAA | |
| Potassium Ion SCHEMBL16267317 | 0.83 | TSHR (0.66) | GPR35TSHRTDP1ALDH1A1GAA | |
| SCHEMBL7791983 | 0.83 | TSHR (0.66) | GPR35TSHRTDP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214547-A1 | BINDING MEMBER TOWARDS PNEUMOLYSIN | GENESTO A/S (DK) | 2009-08-27 | — | — | US | disclosed |
| US-7378504-B2 | Human monoclonal antibodies to Fc gamma receptor I (CD64) | MEDAREX, INC. (US) | 2008-05-27 | — | — | US | disclosed |
| US-20080095784-A1 | Monospecific immunoglobulin for treating autoimmune, cell proliferative and transplant rejection disorders | MEDAREX, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| CN-101061139-A | Binding moieties for pneumolysin | MEDAREX INC (DK) | 2007-10-24 | — | — | CN | disclosed |
| EP-1791867-A2 | BINDING MEMBER TOWARDS PNEUMOLYSIN | GENESTO A/S (DK) | 2007-06-06 | — | — | EP | disclosed |
| EP-1765870-A2 | HUMAN MONOCLONAL ANTIBODIES TO FC GAMMA RECEPTOR I (CD64) | Medarex, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20070003561-A1 | Binding member towards pneumococcus surface adhesin a protein (psaa) | MEDAREX, INC. | 2007-01-04 | — | — | US | disclosed |
| EP-1646654-A1 | BINDING MEMBER TOWARDS PNEUMOCOCCUS SURFACE ADHESIN A PROTEIN (PsaA) | GENESTO A/S (DK) | 2006-04-19 | — | — | EP | disclosed |
| WO-2006021210-A2 | BINDING MEMBER TOWARDS PNEUMOLYSIN | GENESTO A/S (DK) | 2006-03-02 | — | — | WO | disclosed |
| WO-2006002438-A2 | HUMAN MONOCLONAL ANTIBODIES TO FC GAMMA RECEPTOR I (CD64) | MEDAREX, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| WO-2005003174-A1 | BINDING MEMBER TOWARDS PNEUMOCOCCUS SURFACE ADHESIN A PROTEIN (PsaA) | GENESTO A/S (DK) | 2005-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214547-A1 | BINDING MEMBER TOWARDS PNEUMOLYSIN | CD2BP2, C1QBP, CD47 | GPR35 2996/4885TSHR 3667/4885TDP1 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.