SCHEMBL4252836

SCHEMBL4252836

Cc1ccc(-n2c3ccc(-n4c5ccc(C)cc5c5cc(Br)ccc54)cc3c3cc(-n4c5ccc(C)cc5c5cc(Br)ccc54)ccc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 2/20 0.38
MAPT P10636 4/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 1/20 0.37
PDE10A Q9Y233 1/20 0.35
MAPK1 P28482 1/20 0.34
TSHR P16473 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
PIK3CB P42338 1/20 0.34
PIK3CG P48736 1/20 0.34
USP14 P54578 1/20 0.33
KAT2B Q92831 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALOX15 P16050 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2721451 0.97 ALDH1A1 (0.41) DNM1ALDH1A1POLBMAPTKDM4E
SCHEMBL4251581 0.95 DNM1 (0.39) DNM1ALDH1A1POLBMAPTKDM4E
SCHEMBL14845769 0.93 ALDH1A1 (0.41) DNM1ALDH1A1POLBMAPTKDM4E
SCHEMBL356742 0.93 ALDH1A1 (0.44) DNM1ALDH1A1POLBMAPTKDM4E
SCHEMBL13956895 0.90 DNM1 (0.36) DNM1ALDH1A1POLBMAPTKDM4E
SCHEMBL3902452 0.90 DNM1 (0.36) DNM1ALDH1A1POLBMAPTKDM4E
SCHEMBL38654780 0.90 ALDH1A1 (0.44) ALDH1A1POLBMAPTKDM4EGAA
SCHEMBL18674305 0.90 ALDH1A1 (0.44) ALDH1A1POLBMAPTKDM4EGAA
SCHEMBL13231732 0.89 POLB (0.44) ALDH1A1POLBMAPTKDM4EGAA
SCHEMBL15784487 0.89 POLB (0.44) ALDH1A1POLBMAPTKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES NAT1, SAT1, RIF1 DNM1 1173/4885ALDH1A1 529/4885POLB 2158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.