SCHEMBL3902452

SCHEMBL3902452

Cc1ccc2c(c1)c1cc(Br)ccc1n2-c1ccc(-c2ccc(-n3c4ccc(C)cc4c4cc(Br)ccc43)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.36
POLB P06746 1/20 0.35
MAPT P10636 4/20 0.35
PDE10A Q9Y233 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
TSHR P16473 1/20 0.34
MAOB P27338 1/20 0.34
GAA P10253 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KDM4E B2RXH2 1/20 0.34
CA9 Q16790 1/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
PIK3CB P42338 1/20 0.34
PIK3CG P48736 1/20 0.34
USP14 P54578 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13956895 1.00 DNM1 (0.36) DNM1POLBMAPTPDE10AALDH1A1
SCHEMBL4251581 0.95 DNM1 (0.39) DNM1POLBMAPTPDE10AALDH1A1
SCHEMBL14845769 0.93 ALDH1A1 (0.41) DNM1POLBMAPTPDE10AALDH1A1
SCHEMBL2721451 0.93 ALDH1A1 (0.41) DNM1POLBMAPTPDE10AALDH1A1
SCHEMBL4252836 0.90 DNM1 (0.39) DNM1POLBMAPTPDE10AALDH1A1
SCHEMBL356742 0.90 ALDH1A1 (0.44) DNM1POLBMAPTPDE10AALDH1A1
SCHEMBL18674305 0.90 ALDH1A1 (0.44) POLBMAPTALDH1A1MAPK1TSHR
SCHEMBL38654780 0.90 ALDH1A1 (0.44) POLBMAPTALDH1A1MAPK1TSHR
SCHEMBL29447739 0.89 POLB (0.41) POLBMAPTMAPK1TSHRGAA
SCHEMBL12544709 0.89 POLB (0.41) POLBMAPTMAPK1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189636-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-06-15 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
EP-1641894-B1 NOVEL MATERIALS FOR ELECTROLUMINESCENCE MERCK PATENT GMBH (DE) 2009-01-21 EP disclosed
US-20060284140-A1 Novel materials for electroluminescence MERCK PATENT GMBH (DE) 2006-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES NAT1, SAT1, RIF1 DNM1 1173/4885POLB 2158/4885MAPT 1378/4885
US-20230189636-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EMC1, EMC2, EPCAM DNM1 2017/4885POLB 2108/4885MAPT 804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.