SCHEMBL4252913

SCHEMBL4252913

O[Si](O)(C1CCCCC1)[Si](O)(O)C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.35
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TSHR P16473 1/20 0.33
EPHX1 P07099 1/20 0.32
PHGDH O43175 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4254290 0.96 TSHR (0.35) MGLLTSHRALDH1A1
Cyclohexylsilanetriol SCHEMBL78580 0.79 CES2 (0.33) CES2CES1TSHREPHX1ALDH1A1
SCHEMBL2192326 0.79 EPHX1 (0.35) CES2CES1TSHREPHX1ALDH1A1
SCHEMBL9746168 0.79 HDAC8 (0.33) CES2CES1TSHREPHX1ALDH1A1
SCHEMBL9622673 0.79 CES2 (0.33) CES2CES1TSHREPHX1ALDH1A1
SCHEMBL9622146 0.79 EPHX1 (0.35) CES2CES1TSHREPHX1ALDH1A1
SCHEMBL7073146 0.79 EPHX1 (0.35) CES2CES1TSHREPHX1ALDH1A1
SCHEMBL9622434 0.79 CES2 (0.33) CES2CES1TSHREPHX1ALDH1A1
SCHEMBL6114649 0.79 HDAC8 (0.33) CES2CES1TSHREPHX1ALDH1A1
SCHEMBL6115118 0.79 HDAC8 (0.33) CES2CES1TSHREPHX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815339-B2 Surface modifiers and process for surface modifications of particles of metal oxide using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-08-26 US claimed
EP-2062948-B1 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same KOREA INST SCI & TECH (KR) 2013-10-02 EP claimed
EP-2062948-A2 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same Korea Institute of Science and Technology (KR) 2009-05-27 EP claimed
US-20090130306-A1 SURFACE MODIFIERS AND PROCESS FOR SURFACE MODIFICATIONS OF PARTICLES OF METAL OXIDE USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNLOGY (KR) 2009-05-21 US claimed
US-8815339-B2 Surface modifiers and process for surface modifications of particles of metal oxide using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-08-26 US disclosed
EP-2062948-B1 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same KOREA INST SCI & TECH (KR) 2013-10-02 EP disclosed
EP-2062948-A2 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same Korea Institute of Science and Technology (KR) 2009-05-27 EP disclosed
US-20090130306-A1 SURFACE MODIFIERS AND PROCESS FOR SURFACE MODIFICATIONS OF PARTICLES OF METAL OXIDE USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNLOGY (KR) 2009-05-21 US disclosed