SCHEMBL4254290

SCHEMBL4254290

O[Si](O)(C1CCCC1)[Si](O)(O)C1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.31
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4252913 0.96 MGLL (0.35) TSHRALDH1A1MGLL
SCHEMBL9622157 0.77 TSHR (0.35) TSHRALDH1A1
SCHEMBL78792 0.77
SCHEMBL5576040 0.77 TSHR (0.35) TSHRALDH1A1
SCHEMBL80552 0.76 TSHR (0.30) TSHR
SCHEMBL9622673 0.74 CES2 (0.33) TSHRALDH1A1
SCHEMBL6114649 0.74 HDAC8 (0.33) TSHRALDH1A1
Cyclohexylsilanetriol SCHEMBL78580 0.74 CES2 (0.33) TSHRALDH1A1
SCHEMBL9622146 0.74 EPHX1 (0.35) TSHRALDH1A1
SCHEMBL6115118 0.74 HDAC8 (0.33) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815339-B2 Surface modifiers and process for surface modifications of particles of metal oxide using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-08-26 US claimed
US-8815339-B2 Surface modifiers and process for surface modifications of particles of metal oxide using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-08-26 US disclosed
EP-2062948-B1 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same KOREA INST SCI & TECH (KR) 2013-10-02 EP disclosed
EP-2062948-A2 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same Korea Institute of Science and Technology (KR) 2009-05-27 EP disclosed
US-20090130306-A1 SURFACE MODIFIERS AND PROCESS FOR SURFACE MODIFICATIONS OF PARTICLES OF METAL OXIDE USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNLOGY (KR) 2009-05-21 US disclosed