Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 4/20 | 0.51 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853044 | 0.82 | CPA1 (0.52) | CPA1ALDH1A1 | |
| SCHEMBL19852996 | 0.80 | CPA1 (0.50) | CPA1CTSLCTSBALDH1A1 | |
| SCHEMBL1410076 | 0.78 | CPA1 (0.49) | CPA1 | |
| SCHEMBL18764229 | 0.78 | CPA1 (0.49) | CPA1 | |
| SCHEMBL11640449 | 0.76 | ALDH1A1 (0.55) | CTSBALDH1A1 | |
| SCHEMBL19618993 | 0.75 | ALDH1A1 (0.53) | CTSLCTSBALDH1A1 | |
| SCHEMBL15445430 | 0.75 | SLC15A1 (0.49) | CPA1ALDH1A1 | |
| SCHEMBL11639539 | 0.74 | ALDH1A1 (0.51) | CTSBALDH1A1 | |
| SCHEMBL1974104 | 0.74 | SLC15A1 (0.45) | CPA1CTSLCTSBALDH1A1 | |
| SCHEMBL7644552 | 0.73 | ALDH1A1 (0.54) | CTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054375-A2 | PROCESS OF PREPARING A GAMMA-AMINO ACID | Merck Generics (UK) Limited (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008007145-A2 | PROCESS OF PREPARING A GAMMA-AMINO ACID | GENERICS [UK] LIMITED (GB) | 2008-01-17 | — | — | WO | disclosed |