Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853044 | 0.86 | CPA1 (0.52) | CPA1ALDH1A1 | |
| SCHEMBL4253442 | 0.80 | CPA1 (0.51) | CPA1ALDH1A1CTSLCTSB | |
| SCHEMBL19853046 | 0.80 | CPA1 (0.41) | CPA1ALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL15445430 | 0.74 | SLC15A1 (0.49) | CPA1ALDH1A1 | |
| SCHEMBL8436634 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL9548377 | 0.72 | ALDH1A1 (0.50) | ALDH1A1NPC1KMT2ACTSLCTSB | |
| SCHEMBL22831461 | 0.71 | CPA1 (0.47) | CPA1ALDH1A1KMT2ACTSB | |
| SCHEMBL32688448 | 0.71 | CPA1 (0.47) | CPA1ALDH1A1KMT2ACTSB | |
| SCHEMBL19618993 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KMT2ACTSLCTSB | |
| SCHEMBL15437884 | 0.71 | ALDH1A1 (0.45) | CPA1ALDH1A1MEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169125-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2019-06-06 | — | — | US | claimed |
| WO-2018025295-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2018-02-08 | — | — | WO | claimed |
| US-20210276954-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-09-09 | — | — | US | disclosed |
| US-20210276954-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-09-09 | — | — | US | disclosed |
| US-10988446-B2 | Concise process for preparing 3-pyrrolidine carboxylic acid derivatives | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-04-27 | — | — | US | disclosed |
| US-10988446-B2 | Concise process for preparing 3-pyrrolidine carboxylic acid derivatives | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-04-27 | — | — | US | disclosed |
| US-20190169125-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2019-06-06 | — | — | US | disclosed |
| US-20190169125-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2019-06-06 | — | — | US | disclosed |
| WO-2018025295-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2018-02-08 | — | — | WO | disclosed |
| WO-2018025295-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2018-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276954-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | HPD, ALDH18A1, PGA5 | CPA1 404/4885ALDH1A1 227/4885MEN1 3588/4885 |
| US-20190169125-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | HPD, ALDH18A1, PGA5 | CPA1 404/4885ALDH1A1 227/4885MEN1 3588/4885 |
| US-10988446-B2 | Concise process for preparing 3-pyrrolidine carboxylic acid derivatives | HPD, ALDH18A1, PGA5 | CPA1 404/4885ALDH1A1 227/4885MEN1 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.