Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049550 | 0.89 | TARBP2 (0.53) | LMNAPOLBTP53TARBP2PDCD4 | |
| SCHEMBL9096482 | 0.84 | PPARG (0.58) | PPARA | |
| Cuminaldehyde SCHEMBL4262679 | 0.82 | TYR (0.47) | POLBKDM4EHSD17B10SMN1; SMN2PPARA | |
| 2-Naphthaldehyde SCHEMBL5206558 | 0.78 | DRD2 (0.45) | POLBALDH1A1KDM4EMEN1KMT2A | |
| Formic Acid SCHEMBL28387760 | 0.78 | TARBP2 (0.57) | LMNAPOLBTP53TARBP2PDCD4 | |
| SCHEMBL3973849 | 0.76 | ALDH1A1 (0.48) | LMNATP53ALDH1A1MAPTKDM4E | |
| SCHEMBL3538865 | 0.76 | TARBP2 (0.53) | LMNAPOLBTP53TARBP2PDCD4 | |
| SCHEMBL201829 | 0.76 | TARBP2 (0.53) | LMNAPOLBTP53TARBP2PDCD4 | |
| SCHEMBL22678886 | 0.76 | TARBP2 (0.53) | LMNATP53TARBP2PDCD4ALDH1A1 | |
| SCHEMBL28137840 | 0.76 | TARBP2 (0.53) | LMNAPOLBTP53TARBP2PDCD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599453-B1 | 3-METHYL-2- (3- (2-PHENYL-OXAZOL-4-YLMETHOXY)-CYCLOHEXANECARBONYL-AMINO BUTYRIC ACID DERIVATIVES AND RELATED COMPOUNDS AS PPAR MODULATORS FOR THE TREATMENT OF TYPE 2 DIABETES AND ATHEROSCLEROSIS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-05-06 | — | — | EP | disclosed |