Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | UTRN | P46939 | 5/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1051303 | 0.89 | ALDH1A1 (0.51) | DRD2HTR2AHRH1ALDH1A1MEN1 | |
| 2-Naphthaldehyde SCHEMBL4258154 | 0.86 | UTRN (0.40) | DRD2HTR2AHRH1ALDH1A1MEN1 | |
| SCHEMBL4034465 | 0.81 | RAB9A (0.53) | ALDH1A1MEN1POLBKMT2AL3MBTL1 | |
| Cuminaldehyde SCHEMBL4262679 | 0.78 | TYR (0.47) | POLBSMN1; SMN2HSD17B10NOTUMKDM4E | |
| Anisaldehyde SCHEMBL4253513 | 0.78 | LMNA (0.50) | ALDH1A1MEN1POLBKMT2AHPGD | |
| SCHEMBL9520936 | 0.78 | PPARG (0.43) | DRD2HTR2AHRH1ALDH1A1MEN1 | |
| SCHEMBL4253581 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL7486298 | 0.77 | KDM4E (0.46) | DRD2HTR2AHRH1ALDH1A1MEN1 | |
| SCHEMBL7486296 | 0.77 | KDM4E (0.46) | DRD2HTR2AHRH1ALDH1A1MEN1 | |
| SCHEMBL7563293 | 0.75 | KDR (0.60) | KDM4EPPARGPPARAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599452-B1 | 3-(2-PHENYL-OXAZOL-4-YL METHOXY) CYCLOHEXYLMETHOXY ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS USED AS PPAR MODULATORS FOR TREATING TYPE 2 DIABETES AND ARTERIOSCLEROSIS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-06-20 | — | — | EP | disclosed |