Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24034824 | 0.87 | GABRA1 (0.39) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL24869455 | 0.84 | GABRA1 (0.38) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL29714137 | 0.77 | UGT2B7 (0.42) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL10304872 | 0.75 | GABRA1 (0.40) | GABRA1GABRB1GABRB2LMNA | |
| SCHEMBL13818840 | 0.75 | GABRA1 (0.50) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL14117452 | 0.75 | GABRA1 (0.39) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL16860570 | 0.75 | GABRA1 (0.44) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL20150139 | 0.75 | GABRA1 (0.39) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL21035429 | 0.74 | CYP3A4 (0.37) | GABRA1GABRB1GABRB2SLC6A2CYP1A2 | |
| SCHEMBL13368905 | 0.73 | TRPA1 (0.56) | GABRA1GABRB1GABRB2LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834598-B2 | Dielectric copolymer materials | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| WO-2023161168-A1 | AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-08-31 | — | — | WO | disclosed |
| US-20210355381-A1 | DIELECTRIC COPOLYMER MATERIALS | MERCK PATENT GMBH (DE) | 2021-11-18 | — | — | US | disclosed |
| US-20210355383-A1 | DIELECTRIC COPOLYMER MATERIALS | MERCK PATENT GMBH (DE) | 2021-11-18 | — | — | US | disclosed |
| US-8822633-B2 | High bandgap arylene polymers | SUMITOMO CHEMICAL CO., LTD. (JP) | 2014-09-02 | — | — | US | disclosed |
| US-8822633-B2 | High bandgap arylene polymers | SUMITOMO CHEMICAL CO., LTD. (JP) | 2014-09-02 | — | — | US | disclosed |
| US-8822633-B2 | High bandgap arylene polymers | SUMITOMO CHEMICAL CO., LTD. (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20090036622-A1 | High Bandgap Arylene Polymers | SUMATION CO. LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20090036622-A1 | High Bandgap Arylene Polymers | SUMATION CO. LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20090036622-A1 | High Bandgap Arylene Polymers | SUMATION CO. LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| WO-2006091799-A2 | HIGH BANDGAP ARYLENE POLYMERS | SUMATION CO. LTD. (JP) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036622-A1 | High Bandgap Arylene Polymers | PARG, PCBP1, PARN | GABRA1 1175/4885GABRB1 929/4885GABRB2 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.