Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253532 | 0.87 | GABRA1 (0.48) | GABRA1GABRB1GABRB2LMNATRPA1 | |
| SCHEMBL20150139 | 0.85 | GABRA1 (0.39) | GABRA1GABRB1GABRB2LMNATRPA1 | |
| SCHEMBL29538596 | 0.79 | LMNA (0.59) | GABRA1GABRB1GABRB2LMNATRPA1 | |
| SCHEMBL467310 | 0.79 | LMNA (0.59) | GABRA1GABRB1GABRB2LMNATRPA1 | |
| SCHEMBL1685558 | 0.78 | TTR (0.37) | CA1CA2 | |
| SCHEMBL10304872 | 0.75 | GABRA1 (0.40) | GABRA1GABRB1GABRB2LMNA | |
| SCHEMBL5508810 | 0.74 | LMNA (0.58) | GABRA1GABRB1GABRB2LMNATRPA1 | |
| SCHEMBL20133732 | 0.73 | — | — | |
| SCHEMBL24869455 | 0.73 | GABRA1 (0.38) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL12803312 | 0.72 | TTR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834598-B2 | Dielectric copolymer materials | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-20210355381-A1 | DIELECTRIC COPOLYMER MATERIALS | MERCK PATENT GMBH (DE) | 2021-11-18 | — | — | US | disclosed |