Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014375 | 0.85 | SIGMAR1 (0.59) | SIGMAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL6213619 | 0.80 | MAOA (0.52) | TAAR1RAB9ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL445629 | 0.78 | MAPT (0.48) | ALDH1A1CYP3A4IDO1MAOASIGMAR1 | |
| SCHEMBL6014427 | 0.78 | SLC6A2 (0.39) | ATMTAAR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7631772 | 0.74 | NPC1 (0.52) | ATMTAAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL349780 | 0.74 | ALDH1A1 (0.52) | ATMTAAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4874908 | 0.74 | NPC1 (0.52) | ATMTAAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2243709 | 0.74 | NPC1 (0.52) | ATMTAAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17667767 | 0.73 | SIGMAR1 (0.53) | ATMTAAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25047571 | 0.71 | SIGMAR1 (0.55) | ATMTAAR1SIGMAR1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009122351-A2 | ANTI-PARKINSONIAN COMPOUNDS MPPE | KANGWON NATIONAL UNIVERSITY (KR) | 2009-10-08 | — | — | WO | claimed |
| WO-2009128747-A1 | COMPOSITE MATERIAL, PACKAGE AND CARRIER MADE ON THE BASIS OF THE COMPOSITE MATERIAL AND METHOD OF PRODUCING THE COMPOSITE MATERIAL | OLSHANSKIY ALEXANDER IGOREVICH (RU) | 2009-10-22 | — | — | WO | disclosed |