Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COPS5 | Q92905 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873247 | 0.83 | COPS5 (0.49) | COPS5ALDH1A1CYP1A2KDM4EHSD17B10 | |
| SCHEMBL26851680 | 0.79 | COPS5 (0.38) | COPS5ALDH1A1CYP1A2KDM4EHSD17B10 | |
| SCHEMBL4257076 | 0.76 | ALDH1A1 (0.36) | COPS5ALDH1A1CYP1A2KDM4EHSD17B10 | |
| SCHEMBL13609507 | 0.74 | ALDH1A1 (0.53) | COPS5ALDH1A1CYP1A2HSD17B10SMN1; SMN2 | |
| SCHEMBL1549089 | 0.73 | ALDH1A1 (0.54) | ALDH1A1CYP1A2KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL11375087 | 0.73 | ALDH1A1 (0.38) | COPS5ALDH1A1CYP1A2KDM4EHSD17B10 | |
| SCHEMBL1758948 | 0.72 | ALDH1A1 (0.44) | COPS5ALDH1A1CYP1A2KDM4EHSD17B10 | |
| SCHEMBL7763021 | 0.71 | ALDH1A1 (0.33) | COPS5ALDH1A1CYP1A2KDM4EHSD17B10 | |
| SCHEMBL7763024 | 0.71 | ALDH1A1 (0.33) | COPS5ALDH1A1CYP1A2KDM4EHSD17B10 | |
| SCHEMBL8818161 | 0.70 | ALDH1A1 (0.41) | COPS5ALDH1A1CYP1A2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281142-A1 | THIAZOLE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1921074-A1 | THIAZOLE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281142-A1 | THIAZOLE DERIVATIVE | GK, GCKR, AK2 | COPS5 4318/4885ALDH1A1 1817/4885CYP1A2 2841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.