SCHEMBL4254028

SCHEMBL4254028

O=C(O)c1cc(-c2ccccc2)cc(C(=O)O)c1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.60
ACMSD Q8TDX5 3/20 0.59
HNF4A P41235 2/20 0.59
DHFR P00374 1/20 0.59
MCL1 Q07820 1/20 0.59
AKR1C2 P52895 3/20 0.58
AKR1C1 Q04828 3/20 0.58
AKR1C4 P17516 1/20 0.58
AKR1C3 P42330 1/20 0.58
PTPN2 P17706 1/20 0.56
PTPN6 P29350 1/20 0.56
CDC25B P30305 1/20 0.53
ATM Q13315 1/20 0.53
ALDH1A1 P00352 1/20 0.50
ALOX15 P16050 1/20 0.50
DCLRE1A Q6PJP8 1/20 0.47
DCLRE1B Q9H816 1/20 0.47
EGFR P00533 1/20 0.47
KMO O15229 1/20 0.47
DHODH Q02127 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29129813 0.98 PTPN1 (0.58) PTPN1ACMSDHNF4ADHFRMCL1
SCHEMBL29014575 0.89 PTPN1 (0.58) PTPN1ACMSDHNF4ADHFRMCL1
SCHEMBL29045606 0.88 PTPN1 (0.68) PTPN1ACMSDHNF4ADHFRMCL1
SCHEMBL31517182 0.83 PTPN1 (0.52) PTPN1ACMSDHNF4ADHFRMCL1
SCHEMBL6344561 0.83 PTPN1 (0.52) PTPN1ACMSDHNF4ADHFRMCL1
SCHEMBL27999624 0.82 PTPN1 (0.78) PTPN1ACMSDHNF4ADHFRMCL1
SCHEMBL13979801 0.81 KDM4E (0.53) PTPN1ACMSDHNF4ADHFRMCL1
Pyromellitic Acid SCHEMBL27709363 0.80 ACMSD (0.61) PTPN1ACMSDHNF4ADHFRMCL1
SCHEMBL27786187 0.80 PTPN1 (0.58) PTPN1ACMSDHNF4ADHFRMCL1
SCHEMBL830012 0.80 ALDH1A1 (0.48) PTPN1ACMSDHNF4ADHFRMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120053400-A Nanometer autophagy inducing preparation, preparation method and application thereof, and pharmaceutical composition 中国科学院大学 2025-05-30 CN claimed
CN-119857532-A Metal organic framework, preparation method thereof and method for hydrolyzing 2, 5-dimethylfuran 中国石油化工股份有限公司 2025-04-22 CN claimed
CN-119570046-A Modified metal organic framework material and preparation method and application thereof 中国石油化工股份有限公司 2025-03-07 CN claimed
CN-119570045-A Copper-iron bimetallic MOFs material, preparation method and application thereof, and method for preparing N-substituted pyrrole compound 中国石油化工股份有限公司 2025-03-07 CN claimed
CN-119569634-A Process for the preparation of N-substituted pyrrole compounds 中国石油化工股份有限公司 2025-03-07 CN claimed
CN-115216021-B Modified metal organic framework material and preparation method and application thereof 中国石油化工股份有限公司上海石油化工研究院 2024-03-26 CN claimed
CN-114471467-B Truncated polyhedral MOFs@rGO material and preparation method and application thereof 中国石油化工股份有限公司 2024-01-26 CN claimed
CN-114181398-B Hierarchical porous metal organic framework material and preparation method and application thereof 中国石油化工股份有限公司 2023-09-29 CN claimed
CN-115216021-A Modified metal organic framework material and preparation method and application thereof 中国石油化工股份有限公司上海石油化工研究院 2022-10-21 CN claimed
CN-112679965-B Metal organic framework forming body and preparation method and application thereof 中国石油化工股份有限公司 2022-10-11 CN claimed
CN-112903669-A Hydrogen sulfide colorimetric sensor based on mixed node metal organic framework material target-induced mimic enzyme inactivation 商丘师范学院 2021-06-04 CN claimed
CN-112679965-A Metal organic framework forming body and preparation method and application thereof 中国石油化工股份有限公司 2021-04-20 CN claimed
US-10913718-B2 Synthesis and characterization of metal organic frameworks KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2021-02-09 US claimed
CN-110280316-A A kind of metal phosphide and its preparation method and application based on MOF gel 广东工业大学 2019-09-27 CN claimed
US-20190248742-A1 DESIGN, SYNTHESIS AND CHARACTERIZATION OF METAL ORGANIC FRAMEWORKS UNIV KING ABDULLAH SCI & TECH (SA) 2019-08-15 US claimed
US-10273209-B2 Design, synthesis and characterization of metal organic frameworks KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2019-04-30 US claimed
EP-2804889-B1 PROTON-CONDUCTING MEMBRANE, METHOD FOR THEIR PRODUCTION AND THEIR USE IN ELECTROCHEMICAL CELLS BASF SE (DE) 2019-03-13 EP claimed
CN-105642232-B Produce the method for the MOFs of dibenzothiophenes class sulfide in derv fuel to be removed in depth 中国石化扬子石油化工有限公司 2019-03-05 CN claimed
CN-108329485-A Double transmitting group of the lanthanides europium metal-organic framework materials and the preparation method and application thereof 天津师范大学 2018-07-27 CN claimed
CN-105642232-A MOFs method used for deep removing of dibenzothiophene sulfides in automobile diesel oil 中国石化扬子石油化工有限公司 2016-06-08 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10913718-B2 Synthesis and characterization of metal organic frameworks OSTC, ORC3, COXFA4 PTPN1 4442/4885ACMSD 2783/4885HNF4A 1048/4885
US-10273209-B2 Design, synthesis and characterization of metal organic frameworks OSTC, POF1B, ORC3 PTPN1 4335/4885ACMSD 3065/4885HNF4A 986/4885
US-20190248742-A1 DESIGN, SYNTHESIS AND CHARACTERIZATION OF METAL ORGANIC FRAMEWORKS OSTC, POF1B, ORC3 PTPN1 4335/4885ACMSD 3065/4885HNF4A 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.