Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4249834 | 0.99 | DRD2 (0.33) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4253185 | 0.94 | DRD2 (0.34) | DRD2 | |
| Hydrochloric Acid SCHEMBL4255109 | 0.85 | HTR2C (0.31) | — | |
| Hydrochloric Acid SCHEMBL5050453 | 0.78 | DRD2 (0.36) | DRD2DRD3KDM4ELMNA | |
| SCHEMBL4252063 | 0.78 | DRD2 (0.49) | DRD2DRD3KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4856512 | 0.78 | DRD2 (0.41) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4859631 | 0.77 | DRD2 (0.48) | DRD2DRD3KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4853747 | 0.75 | SIGMAR1 (0.44) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4859093 | 0.74 | KDM4E (0.51) | DRD2DRD3KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4855951 | 0.74 | DRD2 (0.38) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156589-A1 | 1,2-DI(CYCLIC GROUP)SUBSTITUTED BENZENE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20060281747-A1 | 1,2-di(cyclic) substituted benzene derivatives | EISAI R&D MANAGEMENT CO., LTD. | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156589-A1 | 1,2-DI(CYCLIC GROUP)SUBSTITUTED BENZENE DERIVATIVE | CCR10, H1-10, VCAM1 | DRD2 746/4885DRD3 638/4885KDM4E 2662/4885 |
| US-20060281747-A1 | 1,2-di(cyclic) substituted benzene derivatives | CCR10, H1-10, CXCL10 | DRD2 768/4885DRD3 610/4885KDM4E 2695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.