Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250578 | 0.85 | RAB9A (0.41) | L3MBTL1HTTMMP2ALDH1A1KDM4E | |
| SCHEMBL2637695 | 0.83 | TP53 (0.47) | L3MBTL1CYP3A4CYP2C19TP53KMT2A | |
| SCHEMBL4074053 | 0.83 | MAPT (0.46) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4247537 | 0.82 | L3MBTL1 (0.58) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL22026433 | 0.82 | L3MBTL1 (0.44) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28760421 | 0.82 | L3MBTL1 (0.53) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL6831468 | 0.82 | TP53 (0.46) | L3MBTL1CYP3A4CYP2C19TP53KMT2A | |
| SCHEMBL1033607 | 0.80 | TP53 (0.44) | L3MBTL1CYP3A4CYP2C19TP53KMT2A | |
| SCHEMBL11792163 | 0.80 | L3MBTL1 (0.51) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9099535 | 0.79 | USP2 (0.57) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127815-A1 | AMINOALYL-IMIDAZOTETRAZINES FOR TREATMENT OF CANCER | THE UNIVERSITY OF BRADFORD (GB) | 2009-10-22 | — | — | WO | disclosed |