Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AOC2 | O75106 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075252 | 0.91 | HDAC3 (0.44) | MAPTMPOCYP3A4GFERKDM5A | |
| SCHEMBL4250578 | 0.85 | RAB9A (0.41) | MAPTKDM4EALDH1A1L3MBTL1HDAC1 | |
| SCHEMBL4254446 | 0.83 | L3MBTL1 (0.50) | CYP3A4KDM4EALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL963723 | 0.77 | HDAC1 (0.61) | MAPTMPOCYP3A4GFERKDM5A | |
| SCHEMBL4079538 | 0.75 | MAPT (0.47) | MAPTMPOCYP3A4GFERKDM5A | |
| SCHEMBL10906239 | 0.73 | HPGD (0.53) | MAPTALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL10906746 | 0.73 | RAB9A (0.52) | MAPTALDH1A1L3MBTL1HDAC1HDAC6 | |
| SCHEMBL343630 | 0.72 | MPO (0.80) | MAPTMPOCYP3A4GFERKDM5A | |
| SCHEMBL2678949 | 0.72 | MPO (0.80) | MAPTMPOCYP3A4GFERKDM5A | |
| SCHEMBL10951350 | 0.71 | HPGD (0.52) | MAPTALDH1A1LMNAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |