SCHEMBL4254554

SCHEMBL4254554

CN(NC(=O)NCc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPID Q08752 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA7 P43166 1/20 0.46
CA14 Q9ULX7 1/20 0.46
RIPK1 Q13546 1/20 0.46
MAPT P10636 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
EPHX1 P07099 1/20 0.44
AKT1 P31749 2/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.43
RAB9A P51151 1/20 0.43
PTPN1 P18031 1/20 0.43
CTSK P43235 2/20 0.43
TP53 P04637 1/20 0.43
KDM4E B2RXH2 2/20 0.43
GAA P10253 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22649519 0.84 AKT1 (0.54) PPIDSMN1; SMN2CA12CA1CA7
SCHEMBL13745279 0.81 PPID (0.49) PPIDSMN1; SMN2CA12CA1CA7
SCHEMBL14531434 0.78 PPID (0.58) PPIDSMN1; SMN2RIPK1MAPTL3MBTL1
SCHEMBL31248355 0.78 PRSS1 (0.52) SMN1; SMN2CA12CA1CA7CA14
SCHEMBL4246507 0.78 AKT1 (0.53) CA12CA1CA7CA14RIPK1
SCHEMBL4152470 0.78 SMN1; SMN2 (0.56) SMN1; SMN2CA12CA1MAPTL3MBTL1
SCHEMBL10583653 0.77 SMN1; SMN2 (0.61) PPIDSMN1; SMN2MAPTL3MBTL1EPHX1
SCHEMBL6988810 0.77 PPID (0.68) PPIDSMN1; SMN2CA12CA1CA7
SCHEMBL13745661 0.76 PPID (0.47) PPIDSMN1; SMN2CA12CA1CA7
SCHEMBL4193440 0.76 CA12 (0.47) PPIDSMN1; SMN2CA12CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 US disclosed
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 US disclosed
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION MYLK2, TNNC1, MYH2 PPID 975/4885SMN1; SMN2 103/4885CA12 3213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.