SCHEMBL13745661

SCHEMBL13745661

CC(C)(C)OC(=O)CN(Cc1ccccc1)NC(=O)NCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPID Q08752 1/20 0.47
AKT1 P31749 3/20 0.46
CTSL P07711 2/20 0.45
CTSB P07858 2/20 0.45
CTSS P25774 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 1/20 0.43
TP53 P04637 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
RIPK1 Q13546 1/20 0.42
PTPN1 P18031 1/20 0.41
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GAA P10253 1/20 0.41
CTSK P43235 1/20 0.41
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13745015 0.93 RAB9A (0.46) PPIDAKT1SMN1; SMN2KDM4ETP53
SCHEMBL23804464 0.86 PPID (0.43) PPIDAKT1CTSLCTSBCTSS
SCHEMBL13745279 0.85 PPID (0.49) PPIDAKT1CTSLCTSBCTSS
SCHEMBL23804493 0.82 HPGD (0.46) PPIDSMN1; SMN2
SCHEMBL13745028 0.81 EPHX1 (0.49) SMN1; SMN2KDM4ETP53PTPN1GAA
SCHEMBL22649519 0.80 AKT1 (0.54) PPIDAKT1CTSLCTSBCTSS
SCHEMBL6988810 0.78 PPID (0.68) PPIDSMN1; SMN2KDM4ETP53CA12
SCHEMBL30343321 0.78 CA2 (0.37) PPIDAKT1CTSLCTSBCTSS
SCHEMBL4254554 0.76 PPID (0.48) PPIDAKT1SMN1; SMN2KDM4ETP53
SCHEMBL782348 0.76 AKT1 (0.55) AKT1CTSLCTSBCTSSRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 US disclosed
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 US disclosed
WO-2007139346-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2007-12-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION MYLK2, TNNC1, MYH2 PPID 975/4885AKT1 3193/4885CTSL 2885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.