SCHEMBL4250591

SCHEMBL4250591

CCCCCOC(=O)C(Cl)C(Cl)C(=O)OCCCCC

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.54
EPHX1 P07099 1/20 0.50
TSHR P16473 4/20 0.48
ALDH1A1 P00352 2/20 0.48
HCAR2 Q8TDS4 2/20 0.47
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
RAD52 P43351 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ATM Q13315 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
FAAH O00519 1/20 0.44
LMNA P02545 1/20 0.44
ACHE P22303 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4254663 0.98 NAAA (0.57) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL2861335 0.93 ALDH1A1 (0.56) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL27713624 0.86 NAAA (0.54) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL27377210 0.86 NAAA (0.46) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL28096325 0.86 NAAA (0.50) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL18252664 0.84 NAAA (0.57) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL1456675 0.84 NAAA (0.57) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL8970879 0.84 NAAA (0.52) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL7625792 0.84 NAAA (0.52) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL425031 0.83 NAAA (0.60) NAAAEPHX1TSHRALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL NAAA 416/4885EPHX1 1076/4885TSHR 1710/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL NAAA 416/4885EPHX1 1076/4885TSHR 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.