Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29268504 | 0.84 | RAB9A (0.60) | RAB9APOLBTDP1MEN1KMT2A | |
| SCHEMBL7933341 | 0.83 | NPC1 (0.58) | RAB9APOLBTDP1MEN1KMT2A | |
| SCHEMBL30381367 | 0.82 | PKM (0.60) | RAB9APOLBTDP1MEN1KMT2A | |
| SCHEMBL30986310 | 0.82 | RAB9A (0.59) | RAB9APOLBTDP1MEN1KMT2A | |
| SCHEMBL30938481 | 0.82 | RAB9A (0.59) | RAB9APOLBTDP1MEN1KMT2A | |
| SCHEMBL5226832 | 0.82 | PKM (0.60) | RAB9APOLBTDP1MEN1KMT2A | |
| SCHEMBL6036198 | 0.82 | RAB9A (0.59) | RAB9APOLBTDP1MEN1KMT2A | |
| SCHEMBL263278 | 0.82 | RAB9A (0.59) | RAB9APOLBTDP1MEN1KMT2A | |
| SCHEMBL4254892 | 0.82 | RAB9A (0.59) | RAB9APOLBTDP1MEN1KMT2A | |
| SCHEMBL8234531 | 0.82 | RAB9A (0.63) | RAB9APOLBTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846430-B1 | NEW MACROLIDES | BASILEA PHARMACEUTICA AG (CH) | 2009-04-01 | — | — | EP | disclosed |