Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 9/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.39 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4254968 | 0.99 | TMEM97 (0.38) | TMEM97SIGMAR1LGMNMEN1CYP2D6 | |
| SCHEMBL4253340 | 0.91 | PTGIR (0.38) | TMEM97SIGMAR1MEN1CYP2D6MAPT | |
| SCHEMBL13806194 | 0.90 | TMEM97 (0.36) | TMEM97SIGMAR1MEN1CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL4261179 | 0.89 | MEN1 (0.38) | TMEM97SIGMAR1MEN1CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL4852893 | 0.88 | MEN1 (0.41) | TMEM97MEN1CYP2D6MAPTKMT2A | |
| SCHEMBL13816596 | 0.88 | TMEM97 (0.38) | TMEM97SIGMAR1LGMNDRD4HRH1 | |
| SCHEMBL4255874 | 0.86 | LGMN (0.52) | TMEM97SIGMAR1LGMNMEN1MAPT | |
| Hydrochloric Acid SCHEMBL4255870 | 0.86 | LGMN (0.51) | TMEM97SIGMAR1LGMNMEN1MAPT | |
| SCHEMBL13806248 | 0.84 | DRD2 (0.37) | TMEM97SIGMAR1MEN1CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL4851096 | 0.83 | DRD2 (0.39) | TMEM97MEN1CYP2D6MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156589-A1 | 1,2-DI(CYCLIC GROUP)SUBSTITUTED BENZENE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156589-A1 | 1,2-DI(CYCLIC GROUP)SUBSTITUTED BENZENE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20060281747-A1 | 1,2-di(cyclic) substituted benzene derivatives | EISAI R&D MANAGEMENT CO., LTD. | 2006-12-14 | — | — | US | disclosed |
| US-20060276465-A1 | 1,2-di(cyclic) substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156589-A1 | 1,2-DI(CYCLIC GROUP)SUBSTITUTED BENZENE DERIVATIVE | CCR10, H1-10, VCAM1 | TMEM97 2255/4885SIGMAR1 934/4885LGMN 4865/4885 |
| US-20060281747-A1 | 1,2-di(cyclic) substituted benzene derivatives | CCR10, H1-10, CXCL10 | TMEM97 2128/4885SIGMAR1 706/4885LGMN 4873/4885 |
| US-20060276465-A1 | 1,2-di(cyclic) substituted benzene compounds | HRH3, CCR10, HRH1 | TMEM97 3031/4885SIGMAR1 2556/4885LGMN 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.