Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 7/20 | 0.38 |
| ▸ | TACR1 | P25103 | 5/20 | 0.37 |
| ▸ | TACR3 | P29371 | 5/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.37 |
| ▸ | ITGAL | P20701 | 3/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255215 | 1.00 | CXCR3 (0.38) | CXCR3TACR1TACR3SGPL1ITGB2 | |
| SCHEMBL4245504 | 0.86 | SGPL1 (0.38) | CXCR3SGPL1SMO | |
| SCHEMBL4245500 | 0.86 | SGPL1 (0.38) | CXCR3SGPL1SMO | |
| SCHEMBL4254428 | 0.85 | SGPL1 (0.41) | CXCR3SGPL1SMO | |
| SCHEMBL4391383 | 0.85 | SGPL1 (0.41) | CXCR3SGPL1SMO | |
| SCHEMBL4251539 | 0.85 | SGPL1 (0.40) | CXCR3SGPL1SMO | |
| SCHEMBL4251536 | 0.85 | SGPL1 (0.40) | CXCR3SGPL1SMO | |
| SCHEMBL4245455 | 0.85 | SGPL1 (0.37) | CXCR3SGPL1SMONR1H2NR1H3 | |
| SCHEMBL4245458 | 0.85 | SGPL1 (0.37) | CXCR3SGPL1SMONR1H2NR1H3 | |
| SCHEMBL4241386 | 0.85 | CXCR3 (0.39) | CXCR3SGPL1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306039-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2009-12-10 | — | — | US | claimed |
| EP-2057124-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM, LLC (BM) | 2009-05-13 | — | — | EP | claimed |
| WO-2008011611-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2008-01-24 | — | — | WO | claimed |
| US-20090306039-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2009-12-10 | — | — | US | disclosed |
| US-20090306039-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2009-12-10 | — | — | US | disclosed |
| US-20090306039-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2009-12-10 | — | — | US | disclosed |
| EP-2057124-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM, LLC (BM) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008011611-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008011611-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306039-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IP6K1, IP6K2, IP6K3 | CXCR3 1268/4885TACR1 4678/4885TACR3 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.