Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255321 | 1.00 | CYP2D6 (0.54) | CYP2D6TDP1L3MBTL1LMNACES2 | |
| SCHEMBL2308229 | 0.84 | CYP2D6 (0.70) | CYP2D6LMNASLC1A2SRCDPP4 | |
| SCHEMBL7519804 | 0.84 | CYP2D6 (0.70) | CYP2D6LMNASLC1A2SRCDPP4 | |
| SCHEMBL7827857 | 0.82 | CYP2D6 (0.74) | CYP2D6TDP1L3MBTL1LMNACES2 | |
| Hydrochloric Acid SCHEMBL5693429 | 0.82 | CYP2D6 (0.67) | CYP2D6LMNASLC1A2SRCDPP4 | |
| SCHEMBL28830240 | 0.79 | LMNA (0.65) | CYP2D6TDP1L3MBTL1LMNACES2 | |
| SCHEMBL3576405 | 0.78 | CYP2D6 (0.56) | CYP2D6LMNASLC1A2SRCDPP4 | |
| SCHEMBL7598177 | 0.78 | LMNA (0.59) | CYP2D6TDP1L3MBTL1LMNACES2 | |
| SCHEMBL5606071 | 0.78 | CYP2D6 (0.56) | CYP2D6LMNASLC1A2SRCDPP4 | |
| SCHEMBL3630110 | 0.78 | CYP2D6 (0.56) | CYP2D6LMNASLC1A2SRCDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143245-B | Anti-scaling material | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2021-02-05 | — | — | CN | disclosed |
| US-8883453-B2 | Codon specific mutagenesis | UNIVERSITY OF MARYLAND (US) | 2014-11-11 | — | — | US | disclosed |
| US-20090004702-A1 | CODON SPECIFIC MUTAGENESIS | UNIVERSITY OF MARYLAND-OFFICE OF TECHNOLOGY COMMERCIALIZATION (US) | 2009-01-01 | — | — | US | disclosed |