Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2308229 | 1.00 | CYP2D6 (0.70) | CYP2D6DPP4SRCLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL5693429 | 0.98 | CYP2D6 (0.67) | CYP2D6DPP4SRCLMNAMAPK1 | |
| SCHEMBL1427487 | 0.88 | CYP2D6 (0.54) | CYP2D6SLC1A2SLC1A3SLC1A1KMT2A | |
| Hydrochloric Acid SCHEMBL1428219 | 0.86 | CYP2D6 (0.52) | CYP2D6SLC1A2SLC1A3SLC1A1KMT2A | |
| SCHEMBL3576405 | 0.85 | CYP2D6 (0.56) | CYP2D6DPP4SRCLMNAMAPK1 | |
| SCHEMBL5606071 | 0.85 | CYP2D6 (0.56) | CYP2D6DPP4SRCLMNAMAPK1 | |
| SCHEMBL3630110 | 0.85 | CYP2D6 (0.56) | CYP2D6DPP4SRCLMNAMAPK1 | |
| SCHEMBL3582437 | 0.85 | CYP2D6 (0.56) | CYP2D6DPP4SRCLMNAMAPK1 | |
| SCHEMBL4255321 | 0.84 | CYP2D6 (0.54) | CYP2D6DPP4SRCLMNAMAPK1 | |
| SCHEMBL4255324 | 0.84 | CYP2D6 (0.54) | CYP2D6DPP4SRCLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1160368-C | Endothelin antegon | 中国人民解放军军事医学科学院毒物药 | 2004-08-04 | — | — | CN | disclosed |
| CN-1155612-C | Endothelin antagon | 中国人民解放军军事医学科学院毒物药 | 2004-06-30 | — | — | CN | disclosed |
| CN-1155611-C | Endothelin antagon | 中国人民解放军军事医学科学院毒物药 | 2004-06-30 | — | — | CN | disclosed |
| US-20020019496-A1 | Ligands for metal affinity chromatography | PEVOW GERALD (US) | 2002-02-14 | — | — | US | disclosed |
| CN-1330076-A | Endothelin antagon | INST OF TOXIC MEDICINES PLA S (CN) | 2002-01-09 | — | — | CN | disclosed |
| CN-1330077-A | Endothelin antegon | INST OF TOXIC MEDICINES PLA S (CN) | 2002-01-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019496-A1 | Ligands for metal affinity chromatography | MLX, RBX1, BRIX1 | CYP2D6 4484/4885DPP4 4338/4885SRC 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.