SCHEMBL4255693

SCHEMBL4255693

Cc1cccc(-c2cc(-c3cccc(C)c3)c3cc(-c4cccc(C)c4)cc(-c4cccc(C)c4)c3c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
MAP4K4 O95819 2/20 0.45
FYN P06241 2/20 0.45
CLK4 Q9HAZ1 2/20 0.45
DYRK1B Q9Y463 2/20 0.45
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
HPGD P15428 2/20 0.43
ALDH1A1 P00352 1/20 0.43
RAB9A P51151 2/20 0.41
DHODH Q02127 1/20 0.41
MAOB P27338 1/20 0.41
KCNA3 P22001 1/20 0.41
ENPP3 O14638 1/20 0.41
CNR2 P34972 2/20 0.40
PGR P06401 1/20 0.40
CNR1 P21554 1/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
CHEK1 O14757 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4254756 0.92 ENPP1 (0.44) ACHEMAP4K4FYNCLK4DYRK1B
SCHEMBL28043529 0.81 ACHE (0.61) ACHEMAP4K4HPGDALDH1A1RAB9A
SCHEMBL30443064 0.81 ACHE (0.61) ACHEMAP4K4HPGDALDH1A1RAB9A
SCHEMBL301247 0.81 ACHE (0.69) ACHEMAP4K4HPGDALDH1A1RAB9A
SCHEMBL29373699 0.81 ACHE (0.69) ACHEMAP4K4HPGDALDH1A1RAB9A
SCHEMBL31471473 0.81 ACHE (0.69) ACHEMAP4K4HPGDALDH1A1RAB9A
SCHEMBL13804241 0.80 GRM5 (0.41) MAP4K4FYNCLK4DYRK1BCA12
SCHEMBL13804238 0.80 GRM5 (0.41) MAP4K4FYNCLK4DYRK1BCA12
SCHEMBL13804240 0.80 GRM5 (0.41) MAP4K4FYNCLK4DYRK1BCA12
SCHEMBL13781520 0.79 CYP11B1 (0.49) CLK4DYRK1BALDH1A1MAOBABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090206742-A1 ORGANIC LIGHT-EMITTING ELEMENT YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY 2009-08-20 US disclosed
EP-2091094-A2 Organic light-emitting element Yamagata Promotional Organization for Industrial Technology (JP) 2009-08-19 EP disclosed
US-20090160326-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ELEMENT USING THE SAME YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) 2009-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090160326-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ELEMENT USING THE SAME L1CAM, ELF3, ELAVL1 ACHE 1823/4885MAP4K4 4102/4885FYN 3109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.